DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment shv and Dnaja2

DIOPT Version :9

Sequence 1:NP_608525.1 Gene:shv / 33220 FlyBaseID:FBgn0031256 Length:354 Species:Drosophila melanogaster
Sequence 2:NP_062768.1 Gene:Dnaja2 / 56445 MGIID:1931882 Length:412 Species:Mus musculus


Alignment Length:347 Identity:135/347 - (38%)
Similarity:182/347 - (52%) Gaps:37/347 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 AGRDFYKILNVKKNANTNEVKKAYRRLAKELHPDKNKDDPDASTKFQDLGAAYEVLSNPDKRKTY 86
            |....|.||.|...|:.||:|||||:||||.|||||   |:|..||:::..||||||||:||:.|
Mouse     5 ADTKLYDILGVPPGASENELKKAYRKLAKEYHPDKN---PNAGDKFKEISFAYEVLSNPEKRELY 66

  Fly    87 DRCGEECLKKEGMMDHGG--DPFSSFFGD--FGFHFGGDGQQQDAPRGADIVMDLYVSLEELYSG 147
            ||.||:.| :||....||  |.||..||.  |||.......:....||.|::..|.||||:||:|
Mouse    67 DRYGEQGL-REGSGGGGGMDDIFSHIFGGGLFGFMGNQSRSRNGRRRGEDMMHPLKVSLEDLYNG 130

  Fly   148 NFVEIVRNKPVTKPA-------SG-TRKCN-CR---QEMVTRNLGPGRFQMIQQTV--------- 191
            ...::..:|.|...|       || .:||: ||   ..::.|.|.||..|.:|...         
Mouse   131 KTTKLQLSKNVLCSACSGQGGKSGAVQKCSACRGRGVRIMIRQLAPGMVQQMQSVCSDCNGEGEV 195

  Fly   192 ------CDECPNVKLVNEERTLEIEVEQGMVDGQETRFVAEGEPHIDGEPGDLIVRVQQMPHPRF 250
                  |.:|...|::.|.:.||:.|::||..||...|..|.:.....||||:::.:|:..|..|
Mouse   196 INEKDRCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGVEPGDIVLLLQEKEHEVF 260

  Fly   251 LRKNDDLYTNVTISLQDALVGFSMEIKHLDGHLVPVTRE--KVTWPGARIRKKGEGMPNFENNNL 313
            .|..:||:....|.|.:||.||....||||...:.|...  ||..||.....:|||||.:.|...
Mouse   261 QRDGNDLHMTYKIGLVEALCGFQFTFKHLDARQIVVKYPPGKVIEPGCVRVVRGEGMPQYRNPFE 325

  Fly   314 TGNLYITFDVEFPKKDLTEEDK 335
            .|:|||.|||:||:.:....||
Mouse   326 KGDLYIKFDVQFPENNWINPDK 347

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
shvNP_608525.1 DnaJ 22..346 CDD:223560 135/347 (39%)
DnaJ 25..87 CDD:278647 35/61 (57%)
DnaJ_C 131..328 CDD:199909 77/225 (34%)
DnaJ_zf 160..>195 CDD:304418 14/61 (23%)
Dnaja2NP_062768.1 PTZ00037 4..412 CDD:240236 135/347 (39%)
CXXCXGXG motif 143..150 1/6 (17%)
CXXCXGXG motif 159..166 3/6 (50%)
CXXCXGXG motif 186..193 0/6 (0%)
CXXCXGXG motif 202..209 2/6 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 365..412
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

Return to query results.
Submit another query.