Protein Alignment shv and DNAJA4

DIOPT Version :10

• Sequence 1: NP_608525.1
• Gene: shv / 33220
• FlyBaseID: FBgn0031256
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: XP_047288792.1
• Gene: DNAJA4 / 55466
• HGNCID: 14885
• Length: 444
• Species: Homo sapiens
• Alignment Length: 378
• Identity: 130/378 - (34%)
• Similarity: 186/378 - (49%)
• Gaps: 69/378 - (18%)

  Fly    16 LVEESFAGRDFYKILNVKKNANTNEVKKAYRRLAKELHPDKNKDD---------PDAST------ 65
            :|:|:    .:|.||.||.:|:..|:|||||:||.:.|||||.|:         ||.|.
Human    30 MVKET----QYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEGEKGHGHLQPDISLYSYSGF 90

  Fly    66 KFQDLGAAYEVLSNPDKRKTYDRCGEECLKKEGMMDHGGDPFSSFFGDFGFHFGGDGQQQDAPRG 130
            .|:.:..||||||:|.||..||:.||:.:|:.|   .|...|||....|...|||.|:.....||
Human    91 SFKLISQAYEVLSDPKKRDVYDQGGEQAIKEGG---SGSPSFSSPMDIFDMFFGGGGRMARERRG 152

  Fly   131 ADIVMDLYVSLEELYSGNFVEIVRNKPVT---------KPASGTRKCN-CR---QEMVTRNLGPG 182
            .::|..|.|:||:||:|...::...|.|.         |..| ..||. |:   .::..:.:|||
Human   153 KNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKGS-VEKCPLCKGRGMQIHIQQIGPG 216

  Fly   183 RFQMIQQTV----------------CDECPNVKLVNEERTLEIEVEQGMVDGQETRFVAEGEPHI 231
            ..|.| |||                |:.|...|::.|::.:|:.||:||.|||:..|..||:...
Human   217 MVQQI-QTVCIECKGQGERINPKDRCESCSGAKVIREKKIIEVHVEKGMKDGQKILFHGEGDQEP 280

  Fly   232 DGEPGDLIVRVQQMPHPRFLRKNDDLYTNVTISLQDALVGFSMEIKHLDGHLVPVTREKVTWPGA 296
            :.||||:|:.:.|..|..|.|:..||...:.|.|.:||.||...||.||..::.:|.:     ..
Human   281 ELEPGDVIIVLDQKDHSVFQRRGHDLIMKMKIQLSEALCGFKKTIKTLDNRILVITSK-----AG 340

  Fly   297 RIRKKG-------EGMPNFENNNLTGNLYITFDVEFPKKDLTEEDK----EAL 338
            .:.|.|       ||||.::.....|.|.|.|.|.||:|.....:|    |||
Human   341 EVIKHGDLRCVRDEGMPIYKAPLEKGILIIQFLVIFPEKHWLSLEKLPQLEAL 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shv	NP_608525.1	DnaJ_bact	25..345	CDD:274090	128/369 (35%)
DNAJA4	XP_047288792.1	PTZ00037	15..441	CDD:240236	130/378 (34%)