DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shv and dnajb11

DIOPT Version :9

Sequence 1:	NP_608525.1	Gene:	shv / 33220	FlyBaseID:	FBgn0031256	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_942116.1	Gene:	dnajb11 / 386709	ZFINID:	ZDB-GENE-031113-9	Length:	360	Species:	Danio rerio

Alignment Length:	351	Identity:	218/351 - (62%)
Similarity:	273/351 - (77%)	Gaps:	7/351 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CLVIIQLSLLLVEESFAGRDFYKILNVKKNANTNEVKKAYRRLAKELHPDKNKDDPDASTKFQDL 70
            |.:::.|.|.:    ||||||||||.|.::|:..::|||||:||.:||||:|:|||:|..||.||
Zfish    12 CFLLLYLILTV----FAGRDFYKILGVSRSASVKDIKKAYRKLALQLHPDRNQDDPNAQDKFADL 72

  Fly    71 GAAYEVLSNPDKRKTYDRCGEECLKKEGMMDHGGDPFSSFFGDFGFHFGGDGQQ--QDAPRGADI 133
            ||||||||:.:|||.||..|||.| |||.....||.||||||||||.|||..|.  :|.|||.||
Zfish    73 GAAYEVLSDEEKRKQYDAYGEEGL-KEGHQSSHGDIFSSFFGDFGFMFGGSRQPAGRDIPRGNDI 136

  Fly   134 VMDLYVSLEELYSGNFVEIVRNKPVTKPASGTRKCNCRQEMVTRNLGPGRFQMIQQTVCDECPNV 198
            |:||.|:|||:|||||||:||.|||.|.|.|.|||||||||.|..||||||||.|:.|||||||:
Zfish   137 VLDLEVTLEEVYSGNFVEVVRIKPVAKEAPGKRKCNCRQEMRTTQLGPGRFQMTQEVVCDECPNI 201

  Fly   199 KLVNEERTLEIEVEQGMVDGQETRFVAEGEPHIDGEPGDLIVRVQQMPHPRFLRKNDDLYTNVTI 263
            ||||||||||:|:|||:.|..|..|:.|||||||||||||..|::.:.||.|.|:.|||||||||
Zfish   202 KLVNEERTLEVEIEQGVRDEMEYPFIGEGEPHIDGEPGDLRFRIKVLKHPVFERRGDDLYTNVTI 266

  Fly   264 SLQDALVGFSMEIKHLDGHLVPVTREKVTWPGARIRKKGEGMPNFENNNLTGNLYITFDVEFPKK 328
            ||.:|||||.::|.|||||.|.:.|:|:|.||:||.|||||:|:|:|||:.|:|.|||||:||::
Zfish   267 SLVEALVGFEVDITHLDGHKVHIVRDKITKPGSRIWKKGEGLPSFDNNNIRGSLIITFDVDFPRE 331

  Fly   329 DLTEEDKEALKKILDQSSINRIYNGL 354
            .|.::.|:.:|::|.|:...::||||
Zfish   332 QLDDQQKDGIKQLLKQAPSQKVYNGL 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shv	NP_608525.1	DnaJ	22..346	CDD:223560	210/325 (65%)
		DnaJ	25..87	CDD:278647	39/61 (64%)
		DnaJ_C	131..328	CDD:199909	134/196 (68%)
		DnaJ_zf	160..>195	CDD:304418	25/34 (74%)
dnajb11	NP_942116.1	DnaJ	24..346	CDD:223560	208/322 (65%)
		DnaJ	27..89	CDD:278647	39/61 (64%)
		DnaJ_C	134..331	CDD:199909	134/196 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596561
Domainoid	1	1.000	284	1.000	Domainoid score	I1604
eggNOG	1	0.900	-	-		E2759_KOG0713
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9464
Inparanoid	1	1.050	452	1.000	Inparanoid score	I1583
OMA	1	1.010	-	-		QHG53793
OrthoDB	1	1.010	-	-		D391896at33208
OrthoFinder	1	1.000	-	-		FOG0007426
OrthoInspector	1	1.000	-	-		oto40300
orthoMCL	1	0.900	-	-		OOG6_105068
Panther	1	1.100	-	-	LDO	PTHR44298
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2491
SonicParanoid	1	1.000	-	-		X5560
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800