Protein Alignment shv and DNAJA1

DIOPT Version :10

• Sequence 1: NP_608525.1
• Gene: shv / 33220
• FlyBaseID: FBgn0031256
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_001530.1
• Gene: DNAJA1 / 3301
• HGNCID: 5229
• Length: 397
• Species: Homo sapiens
• Alignment Length: 394
• Identity: 133/394 - (33%)
• Similarity: 188/394 - (47%)
• Gaps: 72/394 - (18%)

  Fly    16 LVEESFAGRDFYKILNVKKNANTNEVKKAYRRLAKELHPDKNKDDPDASTKFQDLGAAYEVLSNP 80
            :|:|:    .:|.:|.||.||...|:|||||:||.:.|||||   |:...||:.:..||||||:.
Human     1 MVKET----TYYDVLGVKPNATQEELKKAYRKLALKYHPDKN---PNEGEKFKQISQAYEVLSDA 58

  Fly    81 DKRKTYDRCGEECLKKEGMMDHGGDPFSSFFGDFGFHFGGDGQQQDAPRGADIVMDLYVSLEELY 145
            .||:.||:.||:.:|:.|    .|..|.|....|...|||.|:.|...||.::|..|.|:||:||
Human    59 KKRELYDKGGEQAIKEGG----AGGGFGSPMDIFDMFFGGGGRMQRERRGKNVVHQLSVTLEDLY 119

  Fly   146 SGNFVEIVRNKPV-------TKPASGTRKC--NCR---QEMVTRNLGPGRFQMIQQTV------- 191
            :|...::...|.|       .....|..:|  |||   .::....:|||..|.||...
Human   120 NGATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGHG 184

  Fly   192 --------CDECPNVKLVNEERTLEIEVEQGMVDGQETRFVAEGEPHIDGEPGDLIVRVQQMPHP 248
                    |..|...|:|.|::.||:.:::||.|||:..|..||:.....||||:|:.:.|..|.
Human   185 ERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGDQEPGLEPGDIIIVLDQKDHA 249

  Fly   249 RFLRKNDDLYTNVTISLQDALVGFSMEIKHLDGHLVPVTREKVTWPGARIRKKG-------EGMP 306
            .|.|:.:||:..:.|.|.:||.||...|..||...:.:|    :.|| :|.|.|       ||||
Human   250 VFTRRGEDLFMCMDIQLVEALCGFQKPISTLDNRTIVIT----SHPG-QIVKHGDIKCVLNEGMP 309

  Fly   307 NFENNNLTGNLYITFDVEFPKKDLTEEDK-EALKKIL------------DQSSI---------NR 349
            .:......|.|.|.|.|.||:......|| ..|:|:|            ||..:         .|
Human   310 IYRRPYEKGRLIIEFKVNFPENGFLSPDKLSLLEKLLPERKEVEETDEMDQVELVDFDPNQERRR 374

  Fly   350 IYNG 353
            .|||
Human   375 HYNG 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shv	NP_608525.1	DnaJ_bact	25..345	CDD:274090	126/366 (34%)
DNAJA1	NP_001530.1	PTZ00037	2..394	CDD:240236	133/393 (34%)
		CXXCXGXG motif	134..141		0/6 (0%)
		CXXCXGXG motif	150..157		3/6 (50%)
		CXXCXGXG motif	177..184		0/6 (0%)
		CXXCXGXG motif	193..200		2/6 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	352..397		6/27 (22%)