DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shv and DNAJC18

DIOPT Version :9

Sequence 1:	NP_608525.1	Gene:	shv / 33220	FlyBaseID:	FBgn0031256	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_689899.1	Gene:	DNAJC18 / 202052	HGNCID:	28429	Length:	358	Species:	Homo sapiens

Alignment Length:	116	Identity:	45/116 - (38%)
Similarity:	62/116 - (53%)	Gaps:	14/116 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 EESFAG-------RDFYKILNVKKNANTNEVKKAYRRLAKELHPDKNKDDPDASTKFQDLGAAYE 75
            ||...|       |::|:||.|.::|:..|:|||||:||.:.||||| ..|.|:..|:.:|.|:.
Human    68 EEQLLGVQRIKKCRNYYEILGVSRDASDEELKKAYRKLALKFHPDKN-CAPGATDAFKAIGNAFA 131

  Fly    76 VLSNPDKRKTYDRCGEECLKKEGMMDHGGDPFSSFFGD------FGFHFGG 120
            ||||||||..||..|:|.:..........:.:..|..|      |...|||
Human   132 VLSNPDKRLRYDEYGDEQVTFTAPRARPYNYYRDFEADITPEELFNVFFGG 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shv	NP_608525.1	DnaJ	22..346	CDD:223560	43/112 (38%)
		DnaJ	25..87	CDD:278647	31/61 (51%)
		DnaJ_C	131..328	CDD:199909
		DnaJ_zf	160..>195	CDD:304418
DNAJC18	NP_689899.1	DnaJ	82..143	CDD:278647	31/61 (51%)
DNAJC18	NP_689899.1	DUF1977	250..350	CDD:286411
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910