Protein Alignment crq and SCARB2

DIOPT Version :9

• Sequence 1: NP_001245823.1
• Gene: crq / 33219
• FlyBaseID: FBgn0015924
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_005497.1
• Gene: SCARB2 / 950
• HGNCID: 1665
• Length: 478
• Species: Homo sapiens
• Alignment Length: 473
• Identity: 147/473 - (31%)
• Similarity: 241/473 - (50%)
• Gaps: 46/473 - (9%)

  Fly     4 KCCGETQRKVWVFGLGSVFLLL-----GILIVVFWPGIADNLVEDGLTLKPGTDAYESWLEAPIP 63
            :||        .:..|::.|||     .:|:...:....|..:|..:.|:.||:|::||.:.|:|
Human     3 RCC--------FYTAGTLSLLLLVTSVTLLVARVFQKAVDQSIEKKIVLRNGTEAFDSWEKPPLP 59

  Fly    64 IYLSFYMFNWTNPEDIRNPDIKPNFVEMGPYTFLEKHKKENYTFYDN-ATVAYYERRTWFFDPER 127
            :|..||.||.||||:|...: .|...|:||||:.|...|.|..|.|| .|::....:.:.|:.::
Human    60 VYTQFYFFNVTNPEEILRGE-TPRVEEVGPYTYRELRNKANIQFGDNGTTISAVSNKAYVFERDQ 123

  Fly   128 SNGTLD-DMVTAAHAITATVADEMRDQRKIVKKIINFMLNHEGGKLYVTKPVGEWIFEGYQDNIT 191
            |.|... |::...:....||.:  ..|...:::||..||.....||:||..|.|.:: ||:|.|.
Human   124 SVGDPKIDLIRTLNIPVLTVIE--WSQVHFLREIIEAMLKAYQQKLFVTHTVDELLW-GYKDEIL 185

  Fly   192 DFLNLFNTTKIDI-PYKRFGWLADRNESLTYDGLFTIHTGTDDISNLGRLTHWNGKSETGFY-EM 254
            ..:::|   :.|| ||  ||...::|.  |.||.:...||.|...|..::..||||:...:: ..
Human   186 SLIHVF---RPDISPY--FGLFYEKNG--TNDGDYVFLTGEDSYLNFTKIVEWNGKTSLDWWITD 243

  Fly   255 PCGIVNGTTGDMFPPKMNVNDEITIFATDACRFMNLRPRGTYEN-HGLTATKWVGTEETLDSGEN 318
            .|.::|||.||.|.|.:..::.:.:|.:|.||.:.: ....||: .||.|.::....|.|   .|
Human   244 KCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYI-TFSDYESVQGLPAFRYKVPAEIL---AN 304

  Fly   319 YPNQACFCDEARFDECPKTGVVECKACRDKAPIYSSFPHFYLADQSYVDAVSGMKPEKEKHEFFL 383
            ..:.|.||...  ..|..:||:....|::.|||..||||||.||:.:|.|:.||.|.:|.||.|:
Human   305 TSDNAGFCIPE--GNCLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFV 367

  Fly   384 AVEPITGVPVQVHGRIQINMMIEPDDDFDIYRGVQKVLMPMFWFDQYAELSSELASKAKLAIN-- 446
            .:.|:||:.::...|.|||:.::..|||.....::.::.|:.:.::...:..|.||:.|..||
Human   368 DINPLTGIILKAAKRFQINIYVKKLDDFVETGDIRTMVFPVMYLNESVHIDKETASRLKSMINTT 432

  Fly   447 ---------LSSYGIIFG 455
                     :.:.|:.||
Human   433 LIITNIPYIIMALGVFFG 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
crq	NP_001245823.1	CD36	19..470	CDD:307331	145/458 (32%)
SCARB2	NP_005497.1	CD36	28..455	CDD:307331	140/440 (32%)
		Important for interaction with GBA	155..191		14/36 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5605
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.880