DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment crq and scarb2b

DIOPT Version :9

Sequence 1:	NP_001245823.1	Gene:	crq / 33219	FlyBaseID:	FBgn0015924	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	XP_009299911.1	Gene:	scarb2b / 564077	ZFINID:	ZDB-GENE-170406-1	Length:	523	Species:	Danio rerio

Alignment Length:	495	Identity:	150/495 - (30%)
Similarity:	237/495 - (47%)	Gaps:	38/495 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 CCK-CCGETQRKVWVFGLGSVFLLLGILIVVFWPGIADNLVEDGL----TLKPGTDAYESWLEAP 61
            ||. .||         ..|::.||.|  |.:|..|:...|:.:.|    ||..|:..:.:|...|
Zfish     6 CCMYSCG---------AAGALLLLAG--IALFASGLFQTLIHNKLKKEITLTEGSKVFATWKNPP 59

  Fly    62 IPIYLSFYMFNWTNPEDIRNPDIKPNFVEMGPYTFLEKHKKENYTFYDNAT-VAYYERRTWFFDP 125
            .|:|:.|:.||.||||.....:.|....||||||:.|...|.|.:|.||.| ||.|..:.:.|.|
Zfish    60 PPVYMEFFFFNVTNPEAFLKGEAKARLSEMGPYTYREYRPKHNVSFVDNGTKVAAYTPKVFVFVP 124

  Fly   126 ERSNGTLD-DMVTAAHAITATVADEMRDQRKIVKKIINFMLNHEGGKLYVTKPVGEWIFEGYQDN 189
            |:|.|... ||||..:.....|.:.::....:|...::..:...|.::::|..|.|.:: |::|.
Zfish   125 EKSVGDPSVDMVTTVNIPAVAVMNRIKGAGFLVSSAMSLYMKSIGAEMFMTHTVDELLW-GFKDP 188

  Fly   190 ITDFLNLFNTTKIDIPYKRFGWLADRNESLTYDGLFTIHTGTDDISNLGRLTHWNGKSETGFYEM 254
            :...|........:.    ||.:..:|.|  .||.|..|||..:..:.||:..|.|:....|::.
Zfish   189 LLTKLRSIKPETDEF----FGLMLHKNGS--DDGEFVYHTGEHNYLDYGRIFTWKGEKLMSFWKT 247

  Fly   255 -PCGIVNGTTGDMFPPKMNVNDEITIFATDACRFMNLRPRGTYENHGLTATKWVGTEETLDSGEN 318
             ...::|||.|..|.|.:...:.:.:|..|.||.:::|.....|..|:.|.::......|.||.|
Zfish   248 NQSNMINGTDGSAFHPFLTKEERLDVFTADLCRSIHMRFEKEVEVKGIPAYRFTPPRAVLASGTN 312

  Fly   319 YPNQACFCDEARFDECPKTGVVECKACRDKAPIYSSFPHFYLADQSYVDAVSGMKPEKEKHEFFL 383
            .|....||...:  :|...||::...||..||:..|||||:|.|:.||.||.|:.|..|:|:.||
Zfish   313 NPENEGFCLTPK--KCLDDGVLDVSVCRQGAPVVVSFPHFHLGDEKYVQAVEGLSPVHEQHQTFL 375

  Fly   384 AVEPITGVPVQVHGRIQINMMIEPDDDFDIYRGVQKVLMPMFWFDQYAEL---SSELASKAKLAI 445
            .:.|..||||:...|.|||:.:|....|.:.|.::..:.|:.:.::...:   |:|...|..|.:
Zfish   376 DLNPTMGVPVRAMKRAQINIHLERVTGFPMTRNLESTIFPIIFLNESVVIDNASAERIQKLLLVV 440

  Fly   446 NLSSYGIIFGYSMIAFASVFLITGITLTV----TKKWVRR 481
            .|.|:   |...::|...:.||..:.|.|    .|..|:|
Zfish   441 TLVSH---FPLILVALGVILLIVAVILAVRYYQNKTEVKR 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
crq	NP_001245823.1	CD36	19..470	CDD:307331	141/460 (31%)
scarb2b	XP_009299911.1	CD36	30..463	CDD:279474	134/444 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.030