DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment crq and cd36

DIOPT Version :9

Sequence 1:	NP_001245823.1	Gene:	crq / 33219	FlyBaseID:	FBgn0015924	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001002363.1	Gene:	cd36 / 436636	ZFINID:	ZDB-GENE-040718-55	Length:	465	Species:	Danio rerio

Alignment Length:	484	Identity:	133/484 - (27%)
Similarity:	235/484 - (48%)	Gaps:	40/484 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CCGETQRKVWVFG--LGSVFLLLGILIVVFWPGIADNLVEDGLTLKPGTDAYESWLEAPIPIYLS 67
            ||  .||...:.|  ||::..|||.:::.....|..|.|.....|:.||.|:::|....|.:|..
Zfish     3 CC--DQRCALITGAVLGALIALLGGILIPVGDMIIKNTVHKETVLENGTLAFDTWTSVDIAMYRQ 65

  Fly    68 FYMFNWTNPEDIRNPDIKPNFVEMGPYTFLEKH-KKENYTFYDNATVAYYERRTWFFDPERSNGT 131
            |::||..||:.:.:...||..|:.||||:..:: .|.|.||.||.||::.......|:|..|.|:
Zfish    66 FWIFNVENPDKVLSEGSKPVLVQKGPYTYRVRYIPKTNITFNDNNTVSFVLPAGATFEPSMSVGS 130

  Fly   132 LDDMVTAAHAITATVADEMRDQRKIVKKIINFMLNHEGGKLYVTKPVGEWIFEGYQD-NITDFLN 195
            .:|:.|:.:...|.|      .|.|..|:.::::...|..|:..:.|.|.:: ||:| .:...:.
Zfish   131 EEDVFTSLNLAVAGV------YRLIGPKLADWLIRSSGSSLFQNRTVKELLW-GYKDPMLNSLVG 188

  Fly   196 LFNTTKIDIPYKRFGWLADRNESLTYDGLFTIHTGTDDISNLGRLTHWNGKSETGFY-EMPCGIV 259
            .|      .||..           |.||.:|:.||.|||:.:..:..|.|::...:: :..|..:
Zfish   189 AF------YPYNG-----------TVDGPYTVFTGKDDINKVAIIERWQGETSVNYWNDSYCDKI 236

  Fly   260 NGTTGDMFPPKMNVNDEITIFATDACRFMNLRPRGTYENHGLTATKWVGTEETLDSGENYPNQAC 324
            ||:.|..|.|.::..:.:..|:.|.||.::.....|....|:...:::...:.|.|..:.|:..|
Zfish   237 NGSDGSSFHPFLDKKEPLYFFSPDICRSISAEYEATVNLKGIDVYRYLLPVDALASPVSNPDNMC 301

  Fly   325 FC-DEARFDECPKTGVVECKACRDKAPIYSSFPHFYLADQSYVDAVSGMKPEKEKHEFFLAVEPI 388
            :| |......|...|:::..:|:. .|::.|.|||..|.......|.||.|..::|..||.||||
Zfish   302 YCTDHEITRNCTLAGLLDITSCKG-TPVFISLPHFLYASIELQQGVVGMNPNLDEHSIFLDVEPI 365

  Fly   389 TGVPVQVHGRIQINMMIEPDDDFDIYRGVQK-VLMPMFWFDQYAELSSELASKAKLAINLSSYGI 452
            ||..::...|:|:|||..|.||..:...::: .::|:.|.::.|.|..|.|...|..: :|...:
Zfish   366 TGFTLRFSKRLQVNMMYGPSDDIALLNKIKEHTIIPILWLNETAVLDDETAKMFKNEL-ISRMDM 429

  Fly   453 IFGYS---MIAFASVFL--ITGITLTVTK 476
            :.|..   ::..:::||  :.|:.:..:|
Zfish   430 LEGLQIGLLVTGSAIFLGCMIGLIVVCSK 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
crq	NP_001245823.1	CD36	19..470	CDD:307331	125/460 (27%)
cd36	NP_001002363.1	CD36	17..450	CDD:279474	125/458 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820