Protein Alignment crq and Cd36

DIOPT Version :10

• Sequence 1: NP_787957.1
• Gene: crq / 33219
• FlyBaseID: FBgn0015924
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_113749.2
• Gene: Cd36 / 29184
• RGDID: 2301
• Length: 472
• Species: Rattus norvegicus
• Alignment Length: 501
• Identity: 123/501 - (24%)
• Similarity: 235/501 - (46%)
• Gaps: 75/501 - (14%)

  Fly     2 CCKCCGETQRKVWVFGLGSVFLLLGILIVVFWPGIADNLVEDGLTLKPGTDAYESWLEAPIPIYL 66
            |.:.||.....|    :|:|..:.|.:::.....:.:..::..:.|:.||.|:::|::....:|.
  Rat     3 CDRNCGLITGAV----IGAVLAVFGGILMPVGDLLIEKTIKREVVLEEGTIAFKNWVKTGTTVYR 63

  Fly    67 SFYMFNWTNPEDIRNPDIKPNFVEMGPYTFLEKH-KKENYTFYD--NATVAYYERRTWFFDPERS 128
            .|::|:..|||::.....|....:.||||:..:: .|||.| .|  ::||::.:.....|:|..|
  Rat    64 QFWIFDVQNPEEVAKNSSKIKVKQRGPYTYRVRYLAKENIT-QDPKDSTVSFVQPNGAIFEPSLS 127

  Fly   129 NGTLDDMVT--------AAHAITATVADEMRDQRKIVKKIINFMLNHEGGKLYVTKPVGEWIFEG 185
            .||.:|..|        |.|..|          ...|:.::|.::......::.|:.:.|.:: |
  Rat   128 VGTENDNFTVLNLAVAAAPHIYT----------NSFVQGVLNSLIKKSKSSMFQTRSLKELLW-G 181

  Fly   186 YQDNITDFLNLF-----NTTKIDIPYKRFGWLADRNESLTYDGLFTIHTGTDDISNLGRLTHWNG 245
            |:|   .||:|.     .|..:..||..           |.||::.:..|.|:||.:..:..:.|
  Rat   182 YKD---PFLSLVPYPISTTVGVFYPYNN-----------TVDGVYKVFNGKDNISKVAIIDTYKG 232

  Fly   246 KSETGFYEMPCGIVNGTTGDMFPPKMNVNDEITIFATDACRF--------MNLRPRGTYENHGLT 302
            |....::|..|.::|||....|||.:..:..:..|::|.||.        :||:        |:.
  Rat   233 KRNLSYWESYCDMINGTDAASFPPFVEKSRTLRFFSSDICRSIYAVFGSEVNLK--------GIP 289

  Fly   303 ATKWVGTEETLDSGENYPNQACFCDEARF-DECPKTGVVECKACRDKAPIYSSFPHFYLADQSYV 366
            ..::|.......|....|:..|||.|... :.|...||::...|::..|:|.|.|||..|.....
  Rat   290 VYRFVLPANAFASPLQNPDNHCFCTEKVISNNCTSYGVLDIGKCKEGKPVYISLPHFLHASPDVS 354

  Fly   367 DAVSGMKPEKEKHEFFLAVEPITGVPVQVHGRIQINMMIEPDDDFDIYRGVQK-VLMPMFWF--- 427
            :.:.|:.|.:::|..:|.||||||..:|...|:|:|::::|....:..:.::: .::|:.|.
  Rat   355 EPIEGLNPNEDEHRTYLDVEPITGFTLQFAKRLQVNILVKPARKIEALKNLKRPYIVPILWLNET 419

  Fly   428 ----DQYAEL-SSELASKAKLAINLSSYGIIFGYSMIAFASVFLIT 468
                |:.||: .:::..|.|| :.|... ::.|..::.|.: |:|:
  Rat   420 GTIGDEKAEMFRNQVTGKIKL-LGLVEM-VLLGVGVVMFVA-FMIS 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
crq	NP_787957.1	CD36	17..473	CDD:460076	119/486 (24%)
Cd36	NP_113749.2	CD36	14..463	CDD:460076	120/490 (24%)
		Required for interaction with thrombospondins, THBS1 and THBS2. /evidence=ECO:0000250	93..120		7/27 (26%)
		Interaction with PTK2, PXN and LYN. /evidence=ECO:0000250|UniProtKB:P16671	460..472		1/3 (33%)