Protein Alignment crq and Scarb2

DIOPT Version :9

• Sequence 1: NP_001245823.1
• Gene: crq / 33219
• FlyBaseID: FBgn0015924
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_031670.1
• Gene: Scarb2 / 12492
• MGIID: 1196458
• Length: 478
• Species: Mus musculus
• Alignment Length: 473
• Identity: 145/473 - (30%)
• Similarity: 243/473 - (51%)
• Gaps: 46/473 - (9%)

  Fly     4 KCCGETQRKVWVFGLGSVFLLL-----GILIVVFWPGIADNLVEDGLTLKPGTDAYESWLEAPIP 63
            :||        .:..|::.|||     .:|:...:....|..:|..:.|:.||..:.||.:.|:|
Mouse     3 RCC--------FYTAGTLSLLLLVTSVTLLVARVFQKAVDQTIEKNMVLQNGTKVFNSWEKPPLP 59

  Fly    64 IYLSFYMFNWTNPEDIRNPDIKPNFVEMGPYTFLEKHKKENYTFYDN-ATVAYYERRTWFFDPER 127
            :|:.||.||.||||:|...:| |...|:||||:.|...|.|..|.:| .|::....:.:.|:..:
Mouse    60 VYIQFYFFNVTNPEEILQGEI-PLLEEVGPYTYRELRNKANIQFGENGTTISAVTNKAYVFERNQ 123

  Fly   128 SNGTLD-DMVTAAHAITATVADEMRDQRKIVKKIINFMLNHEGGKLYVTKPVGEWIFEGYQDNIT 191
            |.|..: |::...:....||.|  ..|..:::::|..||.....||:|...|.|.:: ||:|.|.
Mouse   124 SVGDPNVDLIRTINIPLLTVVD--LAQLTLLRELIEAMLKAYQQKLFVIHTVHELLW-GYKDEIL 185

  Fly   192 DFLNLFNTTKIDIPYKRFGWLADRNESLTYDGLFTIHTGTDDISNLGRLTHWNGKSETGFYEM-P 255
            ..:::|   |.|:. ..||...:||.  |.||.:...||.|:..|..::..||||:...::.. .
Mouse   186 SLVHIF---KPDVS-PNFGLFYERNG--TNDGEYVFLTGEDNYLNFSKIVEWNGKTSLDWWTTDT 244

  Fly   256 CGIVNGTTGDMFPPKMNVNDEITIFATDACRFMNLRPRGTYEN-HGLTATKW-VGTEETLDSGEN 318
            |.::|||.||.|.|.::.::.:.:|.:|.||.::: ...::|| .||.|.:: |..|...::.||
Mouse   245 CNMINGTDGDSFHPLISKDEVLYLFPSDLCRSVHI-TFSSFENVEGLPAFRYKVPAEILANTSEN 308

  Fly   319 YPNQACFCDEARFDECPKTGVVECKACRDKAPIYSSFPHFYLADQSYVDAVSGMKPEKEKHEFFL 383
                |.||...  ..|..:||:....|::.|||..||||||.||:.:|.|:.||.|.||:||.|:
Mouse   309 ----AGFCIPE--GNCMDSGVLNISICKNGAPIIMSFPHFYQADEKFVSAIKGMHPNKEEHESFV 367

  Fly   384 AVEPITGVPVQVHGRIQINMMIEPDDDFDIYRGVQKVLMPMFWFDQYAELSSELASKAKLAIN-- 446
            .:.|:||:.::...|.|||..:...|||.....::.::.|:.:.::...:..|.|::.|..||
Mouse   368 DINPLTGIILRGAKRFQINTYVRKLDDFVETGDIRTMVFPVMYLNESVLIDKETANQLKSVINTT 432

  Fly   447 ---------LSSYGIIFG 455
                     :.:.|:.||
Mouse   433 LVVTNIPYIIMALGVFFG 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
crq	NP_001245823.1	CD36	19..470	CDD:307331	143/458 (31%)
Scarb2	NP_031670.1	CD36	28..455	CDD:279474	138/440 (31%)
		Important for interaction with GBA	155..191		12/36 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5605
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.880