DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment BBS8 and SEC

DIOPT Version :9

Sequence 1:	NP_608524.1	Gene:	BBS8 / 33217	FlyBaseID:	FBgn0031255	Length:	549	Species:	Drosophila melanogaster
Sequence 2:	NP_187074.1	Gene:	SEC / 819579	AraportID:	AT3G04240	Length:	977	Species:	Arabidopsis thaliana

Alignment Length:	334	Identity:	73/334 - (21%)
Similarity:	124/334 - (37%)	Gaps:	79/334 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 AAAF----NVGDATSKLYQASRLNPTI---YAERETLVKALFQFLYYHEADVQKAHSLCQAVLEV 279
            |:|:    .:.:||....||..|||.:   ::....|:||        :..:.:|:|   ..||.
plant   162 ASAYMRKGRLSEATQCCQQALSLNPLLVDAHSNLGNLMKA--------QGLIHEAYS---CYLEA 215

  Fly   280 ERQKPSGSTGCTLSWWWQ------QQMGRCLLALHYPRRA---EPFLQQSLTSFPHPDTYLLLSR 335
            .|.:|      |.:..|.      .:.|....||.|.:.|   :|         ..||.||.|..
plant   216 VRIQP------TFAIAWSNLAGLFMESGDLNRALQYYKEAVKLKP---------AFPDAYLNLGN 265

  Fly   336 VYQRIKQPERALLVIGEVVDSRPFDVTYRLEQARIHQAMEQQEDALQLYRLAAKLHPINVESLAS 400
            ||:.:.:|                                  .:|:..|:.|.::.|.:..:..:
plant   266 VYKALGRP----------------------------------TEAIMCYQHALQMRPNSAMAFGN 296

  Fly   401 IAVGYFYDNNPEMALMYYRRILSLGAQSPELYCNIALCCLYGGQIDLVLPCFQRALATATQPGQK 465
            ||..|:.....::|:.:|::.||...:..|.|.|:.......|::|..:.|:.:.|  |.||...
plant   297 IASIYYEQGQLDLAIRHYKQALSRDPRFLEAYNNLGNALKDIGRVDEAVRCYNQCL--ALQPNHP 359

  Fly   466 SDIWYNLSFVAVTSGDFNLAKRCLQLCLTSDAQNGAALNNLAVLAAQSGDILGAKSYLNAAKDVM 530
            ..: .||..:.:.......|....:..|.......|..||||::..|.|:...|.|..|....:.
plant   360 QAM-ANLGNIYMEWNMMGPASSLFKATLAVTTGLSAPFNNLAIIYKQQGNYSDAISCYNEVLRID 423

  Fly   531 PDAAEVTTN 539
            |.||:...|
plant   424 PLAADALVN 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BBS8	NP_608524.1	TPR repeat	299..322	CDD:276809	6/25 (24%)
		TPR repeat	327..355	CDD:276809	8/27 (30%)
		TPR_16	331..392	CDD:290168	8/60 (13%)
		TPR repeat	365..389	CDD:276809	3/23 (13%)
		Coatomer_WDAD	<378..519	CDD:281977	32/140 (23%)
		TPR_11	394..457	CDD:290150	13/62 (21%)
		TPR repeat	394..424	CDD:276809	6/29 (21%)
		TPR repeat	429..457	CDD:276809	6/27 (22%)
		TPR_11	465..526	CDD:290150	14/60 (23%)
		TPR repeat	466..493	CDD:276809	3/26 (12%)
		TPR repeat	500..526	CDD:276809	10/25 (40%)
SEC	NP_187074.1	PEP_TPR_lipo	<54..487	CDD:274350	73/334 (22%)
		TPR repeat	54..81	CDD:276809
		TPR repeat	90..115	CDD:276809
		TPR repeat	121..149	CDD:276809
		TPR repeat	154..184	CDD:276809	6/21 (29%)
		TPR repeat	189..217	CDD:276809	7/38 (18%)
		TPR repeat	223..251	CDD:276809	6/27 (22%)
		TPR repeat	257..285	CDD:276809	11/61 (18%)
		TPR repeat	290..320	CDD:276809	6/29 (21%)
		TPR repeat	325..353	CDD:276809	7/29 (24%)
		TPR repeat	359..383	CDD:276809	3/24 (13%)
		TPR repeat	396..421	CDD:276809	9/24 (38%)
		TPR repeat	426..456	CDD:276809	3/7 (43%)
		TPR repeat	461..488	CDD:276809
		Glycosyltransferase_GTB-type	508..944	CDD:415824
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910