DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13690 and rnh-2

DIOPT Version :9

Sequence 1:	NP_608521.1	Gene:	CG13690 / 33213	FlyBaseID:	FBgn0031252	Length:	347	Species:	Drosophila melanogaster
Sequence 2:	NP_495796.1	Gene:	rnh-2 / 266861	WormBaseID:	WBGene00004383	Length:	297	Species:	Caenorhabditis elegans

Alignment Length:	281	Identity:	131/281 - (46%)
Similarity:	177/281 - (62%)	Gaps:	7/281 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 PCMLGVDEAGRGPVLGPMVYGISYCPLESNKALEDLGCADSKQLTEGKRDIIFNDINTKEYATSC 134
            ||:||:||||||||||||||..:..||:.|..|::||..|||.|.|.||:.|||.:|..|.....
Worm    21 PCVLGIDEAGRGPVLGPMVYAAAISPLDQNVELKNLGVDDSKALNEAKREEIFNKMNEDEDIQQI 85

  Fly   135 VGWAVEIISPNTISTSMYRRSKCSLNEVSMDSAMGLIQQAIDAGVNIAEVYVDTVGPPEKYQEKL 199
            :.:|:..:||..||.||.:|.|.||||||.::|:.||:.|:...||:.|:.||||||...||.||
Worm    86 IAYALRCLSPELISCSMLKRQKYSLNEVSHEAAITLIRDALACNVNVVEIKVDTVGPKATYQAKL 150

  Fly   200 LKRFPSFKITVAKKADSTYPIVSAASICAKVTRDHALKVWSFPE-GLVIKDNEFGSGYPGDPVTR 263
            .|.||...|.|.:||||.:||||||||.||||||..|:.|.|.| .:.:.|..:||||||||.|:
Worm   151 EKLFPGISICVTEKADSLFPIVSAASIAAKVTRDSRLRNWQFREKNIKVPDAGYGSGYPGDPNTK 215

  Fly   264 RFLTEYIDLVFGFPRLVRFSWSTAENALADKAYDMEFDEPDSEKPKYAGTKLTKFF--KGTTKSG 326
            :||...::.||||..|||.||.||...:..:.....: |.|.|:.|....::|.:.  |..|
Worm   216 KFLQLSVEPVFGFCSLVRSSWKTASTIVEKRCVPGSW-EDDEEEGKSQSKRMTSWMVPKNET--- 276

  Fly   327 EIIREECRFFKQRHLESVMEF 347
            |::.:...:||:||:.:::.|
Worm   277 EVVPKRNVYFKERHMSNILTF 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13690	NP_608521.1	RNase_HII_eukaryota_like	73..295	CDD:260002	116/222 (52%)
rnh-2	NP_495796.1	RNase_HII_eukaryota_like	24..248	CDD:260002	116/223 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160078
Domainoid	1	1.000	219	1.000	Domainoid score	I1517
eggNOG	1	0.900	-	-		E1_COG0164
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4664
Inparanoid	1	1.050	243	1.000	Inparanoid score	I2084
Isobase	1	0.950	-	0	Normalized mean entropy	S1065
OMA	1	1.010	-	-		QHG62152
OrthoDB	1	1.010	-	-		D1354466at2759
OrthoFinder	1	1.000	-	-		FOG0003820
OrthoInspector	1	1.000	-	-		oto19056
orthoMCL	1	0.900	-	-		OOG6_100555
Panther	1	1.100	-	-	LDO	PTHR10954
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1166
SonicParanoid	1	1.000	-	-		X3184
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750