DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13690 and rnh201

DIOPT Version :9

Sequence 1:	NP_608521.1	Gene:	CG13690 / 33213	FlyBaseID:	FBgn0031252	Length:	347	Species:	Drosophila melanogaster
Sequence 2:	NP_593684.1	Gene:	rnh201 / 2541542	PomBaseID:	SPAC4G9.02	Length:	326	Species:	Schizosaccharomyces pombe

Alignment Length:	313	Identity:	125/313 - (39%)
Similarity:	177/313 - (56%)	Gaps:	23/313 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSDQEDVVVKKEKKCIENIDENDEEPDDVDFKDSGKISSLKALGPFIAGKENSRNTVYLSDV-PD 64
            |.|..|....:|.....|..||:.:.|        :.||:..|.|.:.....:::..|.|.| .|
pombe     1 MKDDHDAWEPEELVSDNNSSENELQED--------QNSSITFLPPSVNKSNPAKSNYYHSTVTDD 57

  Fly    65 ICKDKPCMLGVDEAGRGPVLGPMVYGISYCPLESNKALEDLGCADSKQLTEGKRDIIFNDI-NTK 128
            |.|.:|..|||||||||||||||||.::|||::.:  |.:.|.||||.|...||:.:...| |..
pombe    58 ISKSQPYRLGVDEAGRGPVLGPMVYAVAYCPVDFD--LTNYGFADSKTLASLKREELLKLICNKS 120

  Fly   129 EYATSCVGWAVEIISPNTISTSMYR-RSKCSLNEVSMDSAMGLIQQAIDAGVNIAEVYVDTVGPP 192
            ......|||:...||...::..|.| |:|.:||..:.|:.:.||::..::|:|:.|:||||||||
pombe   121 NELGKNVGWSTMSISARELAAGMLRYRNKYNLNLQAHDTTIDLIKKVYESGINVTEIYVDTVGPP 185

  Fly   193 EKYQEKLLKRFPSFKITVAKKADSTYPIVSAASICAKVTRDHALKVWSFPEGLVIKDNEFGSGYP 257
            ..|||||...||..|:||.|||||.:||||.||||||||||..|:.    ....|:...:||||.
pombe   186 ISYQEKLQAHFPQAKVTVTKKADSLFPIVSLASICAKVTRDIQLEC----ARESIRTENWGSGYS 246

  Fly   258 GDPVTRRFLTEYIDLVFGFP-RLVRFSWSTAENAL-----ADKAYDMEFDEPD 304
            .|..|..:|...:|.:||:. .:||:||.||::.|     :..:.::::.|.|
pombe   247 SDARTTEWLKVNVDKIFGWKGDIVRYSWKTAKDLLELPSKSQSSIEIDWHEDD 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13690	NP_608521.1	RNase_HII_eukaryota_like	73..295	CDD:260002	104/229 (45%)
rnh201	NP_593684.1	RNase_HII_eukaryota_like	66..282	CDD:260002	103/221 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	178	1.000	Domainoid score	I830
eggNOG	1	0.900	-	-		E1_COG0164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H4664
Inparanoid	1	1.050	197	1.000	Inparanoid score	I1017
OMA	1	1.010	-	-		QHG62152
OrthoFinder	1	1.000	-	-		FOG0003820
OrthoInspector	1	1.000	-	-		oto101358
orthoMCL	1	0.900	-	-		OOG6_100555
Panther	1	1.100	-	-	LDO	PTHR10954
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1166
SonicParanoid	1	1.000	-	-		X3184
TreeFam	1	0.960	-	-
	13	12.860