Protein Alignment AP-2alpha and delta-ADR

DIOPT Version :10

• Sequence 1: NP_995607.1
• Gene: AP-2alpha / 33211
• FlyBaseID: FBgn0264855
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: NP_175308.1
• Gene: delta-ADR / 841298
• AraportID: AT1G48760
• Length: 869
• Species: Arabidopsis thaliana
• Alignment Length: 935
• Identity: 190/935 - (20%)
• Similarity: 371/935 - (39%)
• Gaps: 205/935 - (21%)

  Fly    44 INKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLL-GHDIDFGHMEAVNLLSSNKYSEKQIGYL 107
            |::.:..||.:.   |..|...|...:.||.::..| |.|:.:....||.::||:::..|:|||.
plant    35 ISRAVEEIRREI---KATDLSTKSTALHKLSYLAALHGVDMSWAAFHAVEVVSSSRFQHKRIGYQ 96

  Fly   108 FISVLVNTNSDLIRLIIQSIKNDLQSRNPVHVNLALQCIANIGSRDMAESFSNEIPKLLVSGDTM 172
            .|:...|..:.::.||...::.||.|.|...|:|||:|::.||:.|:|...:.|:..||  |.:.
plant    97 AITQSFNDQTSVMLLITNQVRKDLNSANEYEVSLALECLSRIGTHDLARDLTPEVFTLL--GSSK 159

  Fly   173 DVVKQSAALCLLRLFRSSPDIIPGGEWTSRIIHLLNDQHMGVVTAATSLIDALVKRNPDEYKGCV 237
            ..||:.|...:||:|....|.:.  ....|::..|......:::|...:...|..::|   :.|:
plant   160 SFVKKKAIGVVLRVFEKYHDAVK--VCFKRLVENLETSDPQILSAVVGVFCELATKDP---QSCL 219

  Fly   238 NLAVSRLSRIVTASYTDLQDYTYYFVPAPWLSVKLLRLLQNYNPVTEEAGVRARLNETLETILNK 302
            .|| ....:::..|..:            |:.:|:|::.             |:| ..:|..|.|
plant   220 PLA-PEFYKVLVDSRNN------------WVLIKVLKIF-------------AKL-ALIEPRLGK 257

  Fly   303 AQEPPKSKKVQHSNAKNAVLFEAINLIIHSDSEPNLLVR-ACNQLGQFLSNRETNLRYLALESMC 366
            ....|..:.::.:.||:.| ||.:..::.|.|:....|: |..::.:||...:.||:||.|.::.
plant   258 KVAEPICEHMRRTVAKSLV-FECVRTVVSSLSDNEAAVKLAVAKIREFLVEDDPNLKYLGLNALS 321

  Fly   367 HLATSEFSHEEVKKHQEVVILSMKMEKDVSVRQMAVDLLYAMCDRGNAEEIVQEMLNYLETADYS 431
            .:|....  ..|.:::|||:.:|. ::|.:|:..|:.||.||.:..|..||.:.::||...:|..
plant   322 IVAPKHL--WAVLENKEVVVKAMS-DEDPNVKLEALHLLMAMVNEDNVSEISRILMNYALKSDPL 383

  Fly   432 IREEMVLKVAILAEKYA----TDYTWYVDVILNLIRIAGDYVSEEVWYRVIQIVINREEVQGYAA 492
            ...|::..|.....:.|    .|:.||:.::..:.||......|::.:::|.|.:...:.:....
plant   384 FCNEIIFSVLSACSRNAYEIIVDFDWYLSLLGEMARIPHCQRGEDIEHQLIDIGMRVRDARPQLV 448

  Fly   493 KTVFEALQAPACHENM-----VKVGGYILGEFGNLIAGDSRSAPLVQFK---------LLHSKYH 543
            :..:..|..||...|:     :....::.||:             |:|.         ||..:..
plant   449 RVSWALLIDPALLGNLFLHPILSAAAWVSGEY-------------VEFSKNPYETVEALLQPRTD 500

  Fly   544 LCSPMTRALLLSTYIKFINLFPEIRTNIQDVF---RQHSNLRSADAELQQRASE-------YLQL 598
            |..|..:|:.:.:..|.:            ||   ...|:.....:.|.|.:|.       :...
plant   501 LLPPSIKAIYIHSAFKVL------------VFCLGSYFSSQEPTSSSLAQESSSGSLLVNVFTHE 553

  Fly   599 SIVASTDVLATVLEEMPSF-----PERESSIL---AVLKKK--KPGRVPENEIRESKSPA----- 648
            ||::..:|:...|..:..:     .||..::|   :|:|::  :...:.:||...|:..|
plant   554 SILSLVNVIELGLGPLSGYHDVEVQERAKNVLGYISVIKQEIAEQLNLQDNETEASRVTAFMEDV 618

  Fly   649 ------PLTSAAQNNALVNNSHSKLNNSNANTDLLGLSTPP--SNNIGSGSNSNSTLIDVLGDMY 705
                  |:::.||....|.:......|.....::.|....|  |::: |.::..|..:..|....
plant   619 FSEEFGPISATAQEKVCVPDGLELKENLGDLEEICGEHLKPVESDSV-SYTDKISFSVSKLRIRD 682

  Fly   706 GSNSNNNSSAVYNTKKFLFKNNGVLFENEMLQIGVKSEFRQNLGRLGLFY-----------GNKT 759
            ...:.::||..:.....|                  :|.|:   |.|::|           |..:
plant   683 QQEATSSSSPPHEASSLL------------------AEHRK---RHGMYYLTSQKEDQDSNGTSS 726

  Fly   760 QVPLTN----------FNP------------VLQWSAEDALKLNVQMKVVEPTLEAGAQIQQLLT 802
            ..||.|          |||            |::....|..::..|.|....|......:.:.:.
plant   727 DYPLANELANEISQDSFNPKRKPNQSKPRPVVVKLDDGDESRITPQAKTNIQTANDDESLSRAIQ 791

  Fly   803 AECI--------EDYADAPTIEISFRYNGTQQK-FSIKLPLSVNKFFEPTEMNAESFFARWKNLS 858
            :..:        :.|...|.       :|.|:| .|.::         ....|:|....:.|...
plant   792 SALLVKNKGKEKDRYEGNPN-------SGQQEKEESSRI---------ENHQNSEKKKKKKKKKK 840

  Fly   859 GE------QQRSQKVFKAAQPLDLP 877
            ||      .:|..:|..|::.:.:|
plant   841 GEGSSKHKSRRQNEVASASEQVIIP 865

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AP-2alpha	NP_995607.1	Adaptin_N	40..603	CDD:396262	133/588 (23%)
		Alpha_adaptinC2	730..839	CDD:197886	23/150 (15%)
		Alpha_adaptin_C	839..947	CDD:426707	9/45 (20%)
delta-ADR	NP_175308.1	Adaptin_N	31..487	CDD:396262	119/505 (24%)
		HEAT repeat	259..286	CDD:293787	6/27 (22%)
		HEAT repeat	296..326	CDD:293787	9/29 (31%)
		HEAT repeat	335..359	CDD:293787	9/24 (38%)