Protein Alignment AP-2alpha and AT1G31730

DIOPT Version :10

• Sequence 1: NP_995607.1
• Gene: AP-2alpha / 33211
• FlyBaseID: FBgn0264855
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: NP_174454.2
• Gene: AT1G31730 / 840060
• AraportID: AT1G31730
• Length: 938
• Species: Arabidopsis thaliana
• Alignment Length: 817
• Identity: 186/817 - (22%)
• Similarity: 346/817 - (42%)
• Gaps: 170/817 - (20%)

  Fly     5 EGCEVVSPIDQSRGGKESEASADESLLFYCKSKEAEVKRINKELANIRSKFKGDKTLDGYQKKKY 69
            |..::|..|.::|    |:|..|..:|       :||..:.:.|.        :..:...:.|:|
plant    24 EFLDLVKSIGEAR----SKAEEDRIVL-------SEVDILKRRLL--------EPDIPKRKMKEY 69

  Fly    70 VCKLLFIFLLGHDIDFGHMEAVNLLSSNKYSEKQIGYLFISVLVNTNSDLIRLIIQSIKNDLQSR 134
            :.:|::|.:||||..||::.||.:...:....|:.|||.:::.:|.:.|||.||:.:|:.||:|.
plant    70 IIRLVYIEMLGHDASFGYIYAVKMTHDDNLLLKRTGYLAVTLFLNEDHDLIILIVNTIQKDLRSD 134

  Fly   135 NPVHVNLALQCIANIGSRDMAESFSNEIPKLLVSGDTMDVVKQSAALCLLRLFRSSPDIIPGGEW 199
            |.:.|..||..|..:.:.:...:...::.:||  ....:.|::.|.:.|.|..|.||
plant   135 NYLVVCAALNAICRLINEETIPAVLPQVVELL--NHQKEAVRKKAIMALHRFHRKSP-------- 189

  Fly   200 TSRIIHLLN-------DQHMGVVTAATSLIDALVKRNPDEYKGCVNLAVSRLSRIVTASYTDLQD 257
             |.:.||::       |...||:.|....:..|:..:.:.||..|:..||.|.::......  :.
plant   190 -SSVSHLVSNFRKRLCDNDPGVMGATLCPLFDLISEDVNSYKDLVSSFVSILKQVTERRLP--KS 251

  Fly   258 YTYYFVPAPWLSVKLLRLL-------QNYNPVTEEAGVRARLNETLETILNKAQEPPKSKKVQHS 315
            |.|:.:|||::.:|||:::       :|.:.:         ::..|..:..|..        ..:
plant   252 YDYHQMPAPFIQIKLLKIMALLGSGDKNASDI---------MSMVLGDLFRKCD--------SST 299

  Fly   316 NAKNAVLFEAINLIIHSDSEPNLLVRACNQLGQFLSNRETNLRYLALESMCHLATSEFSHEEVKK 380
            |..||:|:|.|..|......|.||..|.:.:.:||.:...||:|:.::.:..|.  :.|.:..::
plant   300 NIGNAILYECIRCISCILPNPKLLEAAADAISKFLKSDSHNLKYMGIDGLGRLI--KISPDIAEQ 362

  Fly   381 HQEVVILSMKMEKDVSVRQMAVDLLYAMCDRGNAEEIVQEMLNY-LETADYSIREEMVLKVAILA 444
            ||..||..:: :.|.::::...:|||.|....|.|.||..|::| :...|...:.|:..:...||
plant   363 HQLAVIDCLE-DPDDTLKRKTFELLYKMTKSSNVEVIVDRMIDYMISINDNHYKTEIASRCVELA 426

  Fly   445 EKYATDYTWYVDVILNLIRIAGDYVSEEVWYRVIQIVINREEVQGY--------------AAKTV 495
            |::|....|::.::..:...|||.|:.:|.:.:::::     .:|:              |.::.
plant   427 EQFAPSNQWFIQIMNKVFEHAGDLVNIKVAHNLMRLI-----AEGFGEDDDDADSKLRLSAVESY 486

  Fly   496 FEALQAPACHENMVKVGGYILGEFGNLIAGDSRSAPLVQFKL-----LHSKYHLCSPMTRALLLS 555
            .:.:..|......::|..::|||:|.  |....||..:..||     .:|..........:.|:.
plant   487 LQLISEPKLPSLFLQVISWVLGEYGT--ADGKYSASYISGKLCDVADAYSSDETVKGYAVSALMK 549

  Fly   556 TYI------KFINLFPEIRTNIQDVFRQHSNLRSADAELQQRASEYLQLSIVASTDVLATVL--- 611
            .|.      :.:::.||.::.|:::...||      .:|||||.| ||..:......:.|:|
plant   550 IYAFEIASGRKVDVLPECQSLIEELLASHS------TDLQQRAYE-LQALLALDARAVETILPLD 607

  Fly   612 ---EEM----------------------PSFPERESSILAVLKKKKP---GRVPENEIR--ESKS 646
               |::                      |...|||.|.:.......|   ..||.:.:|  ..:.
plant   608 ASCEDIEVDKDLSFLNGYIQQAIESGAQPYISERERSGMFETTDYHPQDHHEVPTHALRFEAYEL 672

  Fly   647 PAPLTSAAQNNALV--------NNSH--------SKLNNSNANTDLLGL-----------STPPS 684
            |.|......:|.||        :.||        |:..:|.....|.|:           :|..|
plant   673 PKPSVPPQASNELVPVPEPSYYSESHQPISTSLVSERESSEIKLRLDGVKQKWGRPSYQSTTAAS 737

  Fly   685 NNIGSGSNSNSTLIDVLGDMYGSNSNNNSSAVYNTKK 721
            :.....:|..||..|.   ..||:|:...|: |..||
plant   738 STTPQAANGISTHSDA---GVGSSSSKPRSS-YEPKK 770

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AP-2alpha	NP_995607.1	Adaptin_N	40..603	CDD:396262	142/602 (24%)
		Alpha_adaptinC2	730..839	CDD:197886
		Alpha_adaptin_C	839..947	CDD:426707
AT1G31730	NP_174454.2	Adaptin_N	41..593	CDD:396262	144/613 (23%)
		HEAT repeat	123..148	CDD:293787	10/24 (42%)
		HEAT repeat	157..185	CDD:293787	6/29 (21%)
		HEAT repeat	194..221	CDD:293787	6/26 (23%)