Protein Alignment AP-2alpha and AT5G22780

DIOPT Version :9

• Sequence 1: NP_995607.1
• Gene: AP-2alpha / 33211
• FlyBaseID: FBgn0264855
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: NP_001330127.1
• Gene: AT5G22780 / 832341
• AraportID: AT5G22780
• Length: 1013
• Species: Arabidopsis thaliana
• Alignment Length: 987
• Identity: 377/987 - (38%)
• Similarity: 562/987 - (56%)
• Gaps: 102/987 - (10%)

  Fly    34 CKSKEAEVKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNK 98
            |::||||..|::|||.|||:.||.:|.|..|:|||||.|:|:|.:||:|:||||||||:|:|:.|
plant    17 CQNKEAERLRVDKELGNIRTCFKNEKVLTPYKKKKYVWKMLYIHMLGYDVDFGHMEAVSLISAPK 81

  Fly    99 YSEKQIGYLFISVLVNTNSDLIRLIIQSIKNDLQSRNPVHVNLALQCIANIGSRDMAESFSNEIP 163
            |.|||:||:..|.|:|.|.|.::|.|.:::||:..||.....|||..:.|||.||.|||.:.::.
plant    82 YPEKQVGYIVTSCLLNENHDFLKLAINTVRNDIIGRNETFQCLALTLVGNIGGRDFAESLAPDVQ 146

  Fly   164 KLLVSGDTMDVVKQSAALCLLRLFRSSPDIIPGGEWTSRIIHLLNDQHMGVVTAATSLIDALVKR 228
            |||:|.....:|::.||||||||||.:||.:....|..|:..||:::.:||:|::|||:.|||..
plant   147 KLLISSSCRPLVRKKAALCLLRLFRKNPDAVNVDGWADRMAQLLDERDLGVLTSSTSLLVALVSN 211

  Fly   229 NPDEYKGCVNLAVSRLSRIVTASYTDL-QDYTYYFVPAPWLSVKLLRLLQNYNPVTEEAGVRARL 292
            |.:.|..|:...|..|.|:  |...|: |:||||.:|:|||.||.:|.|| |.|..|:...|..|
plant   212 NHEAYSSCLPKCVKILERL--ARNQDVPQEYTYYGIPSPWLQVKAMRALQ-YFPTIEDPSTRKAL 273

  Fly   293 NETLETILNKAQEPPKSKKVQHSNAKNAVLFEAINLIIHSDSEPNLLVRACNQLGQFLSNRETNL 357
            .|.|:.||   ......|.|..:||.:||||||::|::|.|:|..::.:....||:|:|.||.|:
plant   274 FEVLQRIL---MGTDVVKNVNKNNASHAVLFEALSLVMHLDAEKEMMSQCVALLGKFISVREPNI 335

  Fly   358 RYLALESMCHLATSEFSHEEVKKHQEVVILSMKMEKDVSVRQMAVDLLYAMCDRGNAEEIVQEML 422
            |||.||:|..:.......:.:||||..:|.|:| :.|:|:|:.|:||||.|||..||::||:|:|
plant   336 RYLGLENMTRMLMVTDVQDIIKKHQSQIITSLK-DPDISIRRRALDLLYGMCDVSNAKDIVEELL 399

  Fly   423 NYLETADYSIREEMVLKVAILAEKYATDYTWYVDVILNLIRIAGDYVSEEVWYRVIQIVINREEV 487
            .||.||::|:|||:.||.||||||:|.|.:|||||||.||..|||:||:::|:||:|.|.|.|::
plant   400 QYLSTAEFSMREELSLKAAILAEKFAPDLSWYVDVILQLIDKAGDFVSDDIWFRVVQFVTNNEDL 464

  Fly   488 QGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDSRSAPLVQFKLLHSKYHLCSPMTRAL 552
            |.|||....|.:...|.||.||||..|||||:|:|:|.....:....|.:||.|....|..|..:
plant   465 QPYAASKAREYMDKIAIHETMVKVSAYILGEYGHLLARQPGCSASELFSILHEKLPTVSTPTIPI 529

  Fly   553 LLSTYIKFINLF----PEIRTNIQDVFRQHSNLRSADAELQQRASEYLQLSI--VASTDVLATVL 611
            |||||.|.:...    ||::..:..||:::.:  ..|.|:||||.||.:||.  .|..||||
plant   530 LLSTYAKLLMHAQPPDPELQKKVWAVFKKYES--CIDVEIQQRAVEYFELSKKGPAFMDVLA--- 589

  Fly   612 EEMPSFPERESSILAVLKKKKPGRVPEN------EIRESKSPAPLTSAAQNNALVNNSHSKLNNS 670
             |||.||||:||::     ||...|.:.      ::|..:.|        :||:|......:|.:
plant   590 -EMPKFPERQSSLI-----KKAENVEDTADQSAIKLRAQQQP--------SNAIVLADPQPVNGA 640

  Fly   671 --NANTDLLGLSTPPSNNIGSGSNSNSTLI---------DVLGDMYG------------------ 706
              .....:|..||.|.:...|.|:.|.||.         |:|.|:.|
plant   641 PPPLKVPILSGSTDPESVARSLSHPNGTLSNIDPQTPSPDLLSDLLGPLAIEAPPGAVSYEQHGP 705

  Fly   707 ------------------SNSNNNSSAVYN-TKKF---LFKNNGVLFENEMLQIGVKSEFRQNLG 749
                              ....|....:.| .::|   ..|::|||:|:..:|||:|:|:|.:.|
plant   706 VGAEGVPDEIDGSAIVPVEEQTNTVELIGNIAERFHALCLKDSGVLYEDPHIQIGIKAEWRGHHG 770

  Fly   750 RLGLFYGNKTQVPLTNFNPVLQWSAEDALKLNVQMKVVEPTLEAGAQIQQLLTAECIEDYADAPT 814
            ||.||.|||...|||:...::...|.    |.:.:..|..|:...||:|..|....|....|...
plant   771 RLVLFMGNKNTSPLTSVQALILPPAH----LRLDLSPVPDTIPPRAQVQSPLEVMNIRPSRDVAV 831

  Fly   815 IEISFRYNGTQQKFSIKLPLSVNKFFEPTEMNAESFFARWKNLSGEQQRSQKVFKAAQPLDLPGA 879
            ::.|:::........:::|.::|||.:|.::.:|.||.:|:.:||...:.|:|.:..:||.||..
plant   832 LDFSYKFGTNVVSAKLRIPATLNKFLQPLQLTSEEFFPQWRAISGPPLKLQEVVRGVRPLALPEM 896

  Fly   880 RNKLMGFGMQLLDQVDPNPDNMVCAGIIHTQSQQVG---CLMRLE--PNKQAQMFRLTVRASKET 939
            .|....|.:.:...:||||:|:|.:...:  |:..|   ||.|:|  |..:.|: ||||.:...|
plant   897 ANLFNSFHVTICPGLDPNPNNLVASTTFY--SETTGAMLCLARIETDPADRTQL-RLTVGSGDPT 958

  Fly   940 VTREICDLLTDQ 951
            :|.|:.:.:.:|
plant   959 LTFELKEFIKEQ 970

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AP-2alpha	NP_995607.1	Adaptin_N	40..598	CDD:279882	258/562 (46%)
		Alpha_adaptinC2	730..839	CDD:197886	32/108 (30%)
		Alpha_adaptin_C	839..947	CDD:280460	37/112 (33%)
AT5G22780	NP_001330127.1	Adaptin_N	23..582	CDD:279882	260/567 (46%)
		HEAT repeat	323..347	CDD:293787	13/23 (57%)
		HEAT repeat	359..387	CDD:293787	14/28 (50%)
		HEAT repeat	397..427	CDD:293787	19/29 (66%)
		Alpha_adaptinC2	751..844	CDD:197886	30/96 (31%)
		Alpha_adaptin_C	856..965	CDD:280460	37/111 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	486	1.000	Domainoid score	I83
eggNOG	1	0.900	-	-		E1_COG4354
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5335
Inparanoid	1	1.050	646	1.000	Inparanoid score	I177
OMA	1	1.010	-	-		QHG53727
OrthoDB	1	1.010	-	-		D751651at2759
OrthoFinder	1	1.000	-	-		FOG0002465
OrthoInspector	1	1.000	-	-		otm3231
orthoMCL	1	0.900	-	-		OOG6_101447
Panther	1	1.100	-	-	O	PTHR22780
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1882
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840