Protein Alignment Polr1B and rpoB

DIOPT Version :10

• Sequence 1: NP_476708.1
• Gene: Polr1B / 33210
• FlyBaseID: FBgn0003278
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: NP_051051.1
• Gene: rpoB / 844783
• -ID: -
• Length: 1072
• Species: Arabidopsis thaliana
• Alignment Length: 1283
• Identity: 280/1283 - (21%)
• Similarity: 466/1283 - (36%)
• Gaps: 393/1283 - (30%)

  Fly    15 TNSRPEFKQIPKKLSRHLANLGGPHVDSFDEMLTVGL-DNSAKHMIPNHWLSPAGEKISMKVE-S 77
            |::.|.|.||              ..:.|...:..|| :..||.        |..|.|..::| .
plant     9 TSAIPGFNQI--------------QFEGFYRFIDQGLIEELAKF--------PKIEDIDHEIEFQ 51

  Fly    78 IWIAKPKVPQDVIDVRTREIYP--TDSRQLHVS----------------YSGMCSV--RLGWS-V 121
            :::...::.:.:|..|. .:|.  |.|.:|:||                :.|...:  .||.| |
plant    52 LFVETYQLVEPLIKERD-AVYESLTYSSELYVSAGLIWKTSRNMQEQRIFIGNIPLMNSLGTSIV 115

  Fly   122 NGVQKTPINMDLGEVPIMLRSKACNLGQATPEEMVKHGEHDSEWGGIFVIRGNEKIVRMLIMTRR 186
            ||:.:..||..|....|..:|:..:.|.:     |..|...|:|||...:..::| .|:.....|
plant   116 NGIYRIVINQILQSPGIYYQSELDHNGIS-----VYTGTIISDWGGRLELEIDKK-ARIWARVSR 174

  Fly   187 NHPICVKRSSWKDRGQNFSDLGMLVQTVREDESSLSNVVHYLNNGTAKFMFSHVKRLSYVPVC-- 249
            ...|.:...|        |.:|:.::.:.|:                              ||
plant   175 KQKISILVLS--------SAMGLNLREILEN------------------------------VCYP 201

  Fly   250 -LILKCLMDYTDEEI---YNRLVQGYESDQYYVSCV-------QAMLREVQNENVYTHAQCKSFI 303
             :.|..|.|...::|   .|.:::.|:.    .|||       :::.:|:|.:  :.|.:|:  :
plant   202 EIFLSFLTDKEKKKIGSKENAILEFYQQ----FSCVGGDPIFSESLCKELQKK--FFHQRCE--L 258

  Fly   304 GNLFRARFPEVPEWQ-----PDDDVTDFILRERVMIHLD----------TYEDKFQLIVFMIQKL 353
            |.:.|...    .|:     |.:::  |:|...|:...|          |.:|...|....|:.:
plant   259 GRIGRRNI----NWRLNLNIPQNNI--FLLPRDVLAAADHLIGMKFGMGTLDDMNHLKNKRIRSV 317

  Fly   354 FQCAQGKY-----KVENVDSAMMQEVLLPGHLYQKYLSERVESWVSQVRRCLQKKLTSPDALVTS 413
            ....|.:.     ::|||                      |:..:|...|  .|.:.:|..||||
plant   318 ADLLQDQLGLALARLENV----------------------VKGTISGAIR--HKLIPTPQNLVTS 358

  Fly   414 AVMTQCMRQAGGV------------------GRAIESFLATGNIASRTGLGLMQNSGLVIMAENI 460
            ..:|.......|:                  ||.: |:|..|.:..||
plant   359 TPLTTTYESFFGLHPLSQVLDRTNPLTQIVHGRKL-SYLGPGGLTGRT----------------- 405

  Fly   461 NRMRYMSHFRAIHRGSYFTTMRTTEARQLLPDAWGFICPVHTPDGTPCGLLNHLTLTCEIS---- 521
                  ::||               .|.:.|..:|.|||:.|.:|...||:..|::...|.
plant   406 ------ANFR---------------IRDIHPSHYGRICPIDTSEGINVGLIGSLSIHARIGDWGS 449

  Fly   522 -MRPDPKLVKAIPKHLIDMGMMPLSNRRYLGEKLYVVFLDGKHLGHIHQSEAEKIVDELRYGKIF 585
             ..|..:|.:...|..|.|..:..|...|     |:: ..|..|. :::...|:.....||.:.|
plant   450 LESPFYELFEKSKKARIRMLFLSPSQDEY-----YMI-AAGNSLA-LNRGIQEEQAVPARYRQEF 507

  Fly   586 GTLP------------QMMEIG--FIPFKKNGQFPGLYIATGPARMMRPVWNLKWKRVE--YIGT 634
            .|:.            |...||  .|||.::.......:::...|...|:     .|.|  .:||
plant   508 LTIAWEEVHLRSIFPFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPL-----SRSEKCIVGT 567

  Fly   635 -LEQLYMEIAIDA----------KEMYPDFTTHLELAKTHFMSNLANL-IPMPDYNQSPRNMYQC 687
             ||:   ::|:|:          |.:|.|      ..|..|..|...| ||:..|.:|.:|
plant   568 GLER---QVALDSGVPAIAEHEGKILYTD------TEKIVFSGNGDTLSIPLIMYQRSNKN---- 619

  Fly   688 QMGKQTMGTPCLNWPKQAANKLYRLQTPGTPLFRPVHYDNIQLD-------DFAMGTNAIVAVIS 745
                     .|::            |.|.....:.:....|..|       :.|:|.|.:||.:.
plant   620 ---------TCMH------------QKPQVRRGKCIKKGQILADGAATVGGELALGKNILVAYMP 663

  Fly   746 YTGYDMEDAMIINKAAYERGFAYGSIYKTKF----------LTLDKKSSYFARHPHMP-ELIKHL 799
            :.||:.|||::|::.     ..||.|| |.|          :|...........||:. .|:::|
plant   664 WEGYNFEDAVLISEC-----LVYGDIY-TSFHIRKYEIQTHVTTQGPERITKEIPHLEGRLLRNL 722

  Fly   800 DTDGLPHPGSKLSYGSPLYCYFDGEVATYKVVKMDE--------------KEDCI---------- 840
            |.:|:...||.:..|..|......:||.......::              ||.|:
plant   723 DKNGIVMLGSWVETGDILVGKLTPQVAKESSYAPEDRLLRAILGIQVSTSKETCLKLPIGGRGRV 787

  Fly   841 --VESIRQLGSFDLSPKKMVAITLRVPRPATIGDKFASRAGQKGICSQKYPAEDLPFTESGLIPD 903
              |..:::.|....:| :::.:.:...|...:|||.|.|.|.|||.|:..|.:|:|:.:.|...|
plant   788 IDVRWVQKKGGSSYNP-EIIRVYISQKREIKVGDKVAGRHGNKGIISKILPRQDMPYLQDGRPVD 851

  Fly   904 IVFNPHGFPSRMTIAMMIETMAGKGAAIHGNVYDATPF--RFSEENTAIDYFGKMLEAGGY---- 962
            :||||.|.||||.:..:.|...|...::....|...||  |:.:|.:....|.::.||...
plant   852 MVFNPLGVPSRMNVGQIFECSLGLAGSLLDRHYRIAPFDERYEQEASRKLVFSELYEASKQTANP 916

  Fly   963 -----NYYGTERLYSGVDGREMTADIFFGVVHYQRLRHMVFDKWQVRSTGAVEARTHQPIKGRKR 1022
                 .|.|..|::.|..|......:..|..:..:|.|.|.||...||:|.....|.||::||.:
plant   917 WVFEPEYPGKSRIFDGRTGDPFEQPVIIGKPYILKLIHQVDDKIHGRSSGHYALVTQQPLRGRSK 981

  Fly  1023 GGGVRFGEMERDALISHGAAFLLQDRLFHNSDKTHTLVCHKCGSILAPLQRIVKRNETGGLSSQP 1087
            .||.|.||||..||...|.|.:||:.|.:.||.            :...|.::.....||...:|
plant   982 QGGQRVGEMEVWALEGFGVAHILQEMLTYKSDH------------IRARQEVLGTTIIGGTIPKP 1034

  Fly  1088 DTCRLCGDNSSVSMIEIPFSFKYLVTELSSVNI--------NARFKLN 1127
            :              :.|.||:.||.||.|:.:        ...|::|
plant  1035 E--------------DAPESFRLLVRELRSLALELNHFLVSEKNFQIN 1068

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Polr1B	NP_476708.1	RNA_pol_B_RPB2	35..1125	CDD:238353	273/1259 (22%)
		RNA_pol_Rpa2_4	564..619	CDD:462028	13/68 (19%)
rpoB	NP_051051.1	rpoB	1..1072	CDD:214330	280/1283 (22%)