Protein Alignment RpI135 and RpIII128

DIOPT Version :9

• Sequence 1: NP_476708.1
• Gene: RpI135 / 33210
• FlyBaseID: FBgn0003278
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: NP_523706.1
• Gene: RpIII128 / 36289
• FlyBaseID: FBgn0004463
• Length: 1137
• Species: Drosophila melanogaster
• Alignment Length: 1191
• Identity: 327/1191 - (27%)
• Similarity: 548/1191 - (46%)
• Gaps: 167/1191 - (14%)

  Fly    10 TIPV--LTNSRPEFKQIPKKLSRHLANLGGPHVDSFDEMLTVGLDNSAKHMIPNHWLSPAGEKI- 71
            ::|:  ||.   ::|.:|..|  .:..|...|:|||:..:.|.:....|   .|..::...:.:
  Fly    25 SVPIKPLTE---KWKLVPAFL--QVKGLVKQHIDSFNHFINVDIKKIVK---ANELVTSGADPLF 81

  Fly    72 SMKVESIWIAKPKVPQDVIDVRTREIYPTDSRQLHVSYSGMCSVRLGWSVNGVQKTP-INMDLGE 135
            .:|...:.:.||.: .|..:: |:...|.:.|....:||...:|.:.:: .|.|:.. .|:.:|.
  Fly    82 YLKYLDVRVGKPDI-DDGFNI-TKATTPHECRLRDTTYSAPITVDIEYT-RGTQRIKRNNLLIGR 143

  Fly   136 VPIMLRSKACNLGQATPEEMVKHGEHDSEWGGIFVIRGNEKIVRMLIMTRRNHPICVKRSSW-KD 199
            :|:|||...|.|...:..|:.|..|...:.||.||:||.||::           :..::.|| |.
  Fly   144 MPLMLRCSNCALTGKSEFELSKLNECPLDPGGYFVVRGQEKVI-----------LIQEQLSWNKM 197

  Fly   200 RGQNFSDLGMLVQTVREDESSLSNVVHYLNNGTAKFMFSHVKRLSYVPVCLILKCLMDYTDEEIY 264
            ..::|:.: :..|.........|..:....:|  |:...|......:|:.:|.|.|...:|:||.
  Fly   198 LTEDFNGV-VQCQVTSSTHEKKSRTLVLSKHG--KYYLKHNSMTDDIPIVVIFKALGVVSDQEIQ 259

  Fly   265 NRL-VQGYESDQYYVSCVQAMLREVQNENVYTHAQCKSFIGN-LFRARFPEVPEWQPDDDVTDFI 327
            :.: :.....:::..|.:.|     .|..|:|..:...::|: |...||.......|.::..:.:
  Fly   260 SLIGIDSKSQNRFGASLIDA-----YNLKVFTQQRALEYMGSKLVVKRFQSATTKTPSEEARELL 319

  Fly   328 LRERVMIHLDTYEDKFQL------IVFMIQKLFQCAQGKYKVENVDSAMMQEVLLPGHLYQKYLS 386
            | ..::.|:..  |.|.|      :..|::::......|...::.|....:.:.|.|.|......
  Fly   320 L-TTILAHVPV--DNFNLQMKAIYVSMMVRRVMAAELDKTLFDDRDYYGNKRLELAGSLLSMMFE 381

  Fly   387 ERVESWVSQVRRCLQKKLTSPDALVTSAVMTQCMRQAGGVGRAIESFLATGNIASRTGLGLMQNS 451
            :..:....:::....|.:  |........:.:.|| |..:...:||.:::||...:.  ..|:.:
  Fly   382 DLFKRMNWELKTIADKNI--PKVKAAQFDVVKHMR-AAQITAGLESAISSGNWTIKR--FKMERA 441

  Fly   452 GLVIMAENINRMRYMSHFRAIHR--GSYFTTMRTTEARQLLPDAWGFICPVHTPDGTPCGLLNHL 514
            |   :.:.::|:.|:|....:.|  ..:..|.:.:..|.|.|..||.:||..||:|..|||:.:|
  Fly   442 G---VTQVLSRLSYISALGMMTRVNSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNL 503

  Fly   515 TL----TCEISMRPDPKLVKAIPKHLIDMGMM---PLSNRRYLGEKLYVVFLDGKHLG----HIH 568
            .|    |.|:..|  |.::.|....:.|:..:   |::|     ..:::||::|..||    |.|
  Fly   504 ALMTHITTEVEER--PVMIVAFNAGVEDIREVSGNPINN-----PNVFLVFINGNVLGLTLNHKH 561

  Fly   569 QSEAEKIVDELRYGKIFGTLPQMMEIGFIPFKKNGQFPGLYIATGPARMMRPVWNLKWKR----- 628
                  :|..|||.:..|.:...:.:.....::     .:||.|...|:.||...::.:|
  Fly   562 ------LVRNLRYMRRKGRMGSYVSVHTSYTQR-----CIYIHTDGGRLCRPYVIVENRRPLVKQ 615

  Fly   629 ---------------------VEYIGTLEQLYMEIAIDAKEMYPDFTTHLELAKTHFMSNLANLI 672
                                 :||:...|:....||.: ::...|.|||||:.....:...|.|:
  Fly   616 HHLDELNRGIRKFDDFLLDGLIEYLDVNEENDSFIAWN-EDQIEDRTTHLEIEPFTLLGVCAGLV 679

  Fly   673 PMPDYNQSPRNMYQCQMGKQTMGTPCLNWPKQAANKLYRLQTPGTPLFRPVHYDNIQLDDFAMGT 737
            |.|.:||||||.|||.||||.||....|...:..:.:|.|..|..|:.:....:....|....|.
  Fly   680 PYPHHNQSPRNTYQCAMGKQAMGMIGYNQKNRIDSLMYNLVYPHAPMVKSKTIELTNFDKLPAGQ 744

  Fly   738 NAIVAVISYTGYDMEDAMIINKAAYERGFAYGSIYKTKFLTLDKKSSY-FAR--HPHMPEL---- 795
            ||.|||:||:|||:|||:|:|||:.:||:....:||....|:.:.::. |.|  .|....|
  Fly   745 NATVAVMSYSGYDIEDALILNKASIDRGYGRCLVYKNSKCTVKRYANQTFDRIMGPMKDALTNKV 809

  Fly   796 -IKH--LDTDGLPHPGSK--------------LSYGSPLYCYFDGEVA--TYKVVKMDEK--EDC 839
             .||  |||||:..||.:              ::..:||    .|:.|  .|..|.:..|  |..
  Fly   810 IFKHDVLDTDGIVAPGEQVQNKQIMINKEMPAVTSMNPL----QGQSAQVPYTAVPISYKGPEPS 870

  Fly   840 IVESIRQLGSFDLSPKKMVAITLRVPRPATIGDKFASRAGQKGICSQKYPAEDLPFTESGLIPDI 904
            .:|  |.:.|.:.....::.|.||..|...|||||:||.||||:.......||:||.:.|:.||:
  Fly   871 YIE--RVMVSANAEEDFLIKILLRQTRIPEIGDKFSSRHGQKGVTGLIVEQEDMPFNDFGICPDM 933

  Fly   905 VFNPHGFPSRMTIAMMIETMAGKGAAIHGNVYDATPFRFSEENTAIDYFGKMLEAGGYNYYGTER 969
            :.||||||||||:...:|.:.||...:.|..:..|.|..|:    ::.....||..|:||.|.:.
  Fly   934 IMNPHGFPSRMTVGKTLELLGGKAGLLEGKFHYGTAFGGSK----VEDIQAELERHGFNYVGKDF 994

  Fly   970 LYSGVDGREMTADIFFGVVHYQRLRHMVFDKWQVRSTGAVEARTHQPIKGRKRGGGVRFGEMERD 1034
            .|||:.|..:.|.|:.|.|:||:|:|||.||...|:.|.....|.||.:||.|.||:|.||||||
  Fly   995 FYSGITGTPLEAYIYSGPVYYQKLKHMVQDKMHARARGPKAVLTRQPTQGRSREGGLRLGEMERD 1059

  Fly  1035 ALISHGAAFLLQDRLFHNSDKTHTLVCHKCGSILAPLQRIVKRNETGGLSSQPDTCRLCGDNSSV 1099
            .|||:||:.|:.:||..:||.....||..||.:                 :....|..|..:::|
  Fly  1060 CLISYGASMLIMERLMISSDAFEVDVCRTCGRM-----------------AYCSWCHFCQSSANV 1107

  Fly  1100 SMIEIPFSFKYLVTELSSVNI 1120
            |.|.:|::.|.|..||:|:|:
  Fly  1108 SKISMPYACKLLFQELTSMNV 1128

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RpI135	NP_476708.1	RpoB	34..1128	CDD:223163	321/1165 (28%)
		RNA_pol_B_RPB2	35..1125	CDD:238353	321/1164 (28%)
		RNA_pol_Rpa2_4	564..614	CDD:284335	12/53 (23%)
RpIII128	NP_523706.1	PRK08565	34..1135	CDD:236291	324/1179 (27%)
		RNA_pol_B_RPB2	47..1133	CDD:238353	321/1164 (28%)
		RNA_pol_Rpb2_2	210..370	CDD:282427	29/169 (17%)
		RNA_pol_Rpb2_4	546..607	CDD:282431	18/71 (25%)
		RNA_pol_Rpb2_5	628..668	CDD:282432	11/40 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448990
Domainoid	1	1.000	152	1.000	Domainoid score	I186
eggNOG	1	0.900	-	-		E1_COG0085
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D42570at2759
OrthoFinder	1	1.000	-	-		FOG0000346
OrthoInspector	1	1.000	-	-		otm51329
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR20856
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.850