Protein Alignment RpI135 and Polr3b

DIOPT Version :9

• Sequence 1: NP_476708.1
• Gene: RpI135 / 33210
• FlyBaseID: FBgn0003278
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: NP_001178807.1
• Gene: Polr3b / 362858
• RGDID: 1565311
• Length: 1133
• Species: Rattus norvegicus
• Alignment Length: 1179
• Identity: 343/1179 - (29%)
• Similarity: 539/1179 - (45%)
• Gaps: 184/1179 - (15%)

  Fly    39 HVDSFDEMLTVGLDNSAKHMIPNHWLSPAGEKISMKVESIWIAK--------PKVPQDVIDVRTR 95
            |:|||:..:.|.:....|          |.||::...:.:|..|        |.| ::..:| ||
  Rat    43 HIDSFNYFINVEIKKIMK----------ANEKVTSDADPMWYLKYLNIYVGLPDV-EESFNV-TR 95

  Fly    96 EIYPTDSRQLHVSYSGMCSVRLGWSVNGVQKTPIN-MDLGEVPIMLRSKACNLGQATPEEMVKHG 159
            .:.|.:.|...::||...:|.:.:: .|.|:...| :.:|.:||||||..|.|...||.|..|..
  Rat    96 PVSPHECRLRDMTYSAPITVDIEYT-RGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLN 159

  Fly   160 EHDSEWGGIFVIRGNEKIVRMLIMTRRNHPICVKRSSWKDRGQNFSDLGMLVQTVREDESSLSNV 224
            |...:.||.|:::|.||::.:.....:|..|.        .......:|..|.:...::.|.:|:
  Rat   160 ECPLDPGGYFIVKGVEKVILIQEQLSKNRIIV--------EADRKGAVGASVTSSTHEKKSRTNM 216

  Fly   225 VHYLNNGTAKFMFSHVKRLSYVPVCLILKCLMDYTDEEIYNRLVQGYESDQYYVSCVQAMLREVQ 289
            .  :..|  :|...|......:|:.:|.|.:...:|:||    ||...::::.::.....|.|.|
  Rat   217 A--VKQG--RFYLRHNTLSEDIPIVIIFKAMGVESDQEI----VQMIGTEEHVMAAFGPSLEECQ 273

  Fly   290 NENVYTHAQCKSFIGNLFR-----------ARFPEVPEWQPDDDVTDFILRERVMIHLDTYEDKF 343
            ...::|..|...:|||..|           .:..|..|          :|...::.|:...|..|
  Rat   274 KAQIFTQMQALKYIGNKVRRQRMWGGGPKKTKIEEARE----------LLASTILTHVPVKEFNF 328

  Fly   344 Q----LIVFMIQKLFQCAQGKYKVENVDSAMMQEVLLPGHLYQKYLSERVESWVSQVRRCLQKKL 404
            :    ....|::::. .|||..||::.|....:.:.|.|.|......:..:.:.|::::...:.:
  Rat   329 RAKCIYTAVMVRRVI-LAQGDNKVDDRDYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVI 392

  Fly   405 TSPDALVTSAVMTQCMRQ---AGGVGRAIESFLATGNIASRTGLGLMQNSGLVIMAENINRMRYM 466
              |........:.:.|||   ..|:..||    :|||.:.:.  ..|...|   :.:.::|:.|:
  Rat   393 --PKQRAAQFDVVKHMRQDQITNGMVNAI----STGNWSLKR--FKMDRQG---VTQVLSRLSYI 446

  Fly   467 SHFRAIHR--GSYFTTMRTTEARQLLPDAWGFICPVHTPDGTPCGLLNHLTLTCEIS--MRPDPK 527
            |....:.|  ..:..|.:.:..|.|.|..||.:||..||:|..|||:.:|.|...|:  |...|.
  Rat   447 SALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPI 511

  Fly   528 LVKAIPKHLIDMGMMPLSNRRYLGEKL-----YVVFLDGKHLGHIHQSEAEKIVDELRYGKIFGT 587
            :..|....:.|:.::       .||:|     ::|||:|..||.|.  :.:|:|...|..:..|.
  Rat   512 IKLAGNLGVEDVNLL-------CGEELSYPNVFLVFLNGNILGVIR--DHKKLVSTFRLMRRAGY 567

  Fly   588 LPQMMEIGFIPFKKNGQFPGLYIATGPARMMRPVWNLKWKR------------------------ 628
            :.:     |:....|.....:||::...|:.||...:|.::
  Rat   568 INE-----FVSISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHE 627

  Fly   629 --VEYIGTLEQLYMEIAIDAKEMYPDFTTHLELAKTHFMSNLANLIPMPDYNQSPRNMYQCQMGK 691
              |||:...|:....||:....:..| |||||:.....:...|.|||.|.:||||||.|||.|||
  Rat   628 SLVEYLDVNEENDCNIALYEHTINKD-TTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGK 691

  Fly   692 QTMGTPCLNWPKQAANKLYRLQTPGTPLFRPVHYDNIQLDDFAMGTNAIVAVISYTGYDMEDAMI 756
            |.|||...|...:....:|.|..|..|:.:....:.|..:....|.||.|||:||:|||:|||::
  Rat   692 QAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIDFEKLPAGQNATVAVMSYSGYDIEDALV 756

  Fly   757 INKAAYERGFAYGSIYKTKFLTLDKKSSY------------FARHPHMPELIKH--LDTDGLPHP 807
            :|||:.:|||....:||....||.:.::.            ..|.|    :.:|  ||.||:..|
  Rat   757 LNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKP----IWRHEILDADGICSP 817

  Fly   808 GSKL---------SYGSPLYCYFDG----EVATYKVVKMDEK--EDCIVESIRQLGSFDLSPKKM 857
            |.|:         |..:......:|    :...||.|.:..|  .|..:|.:  :.|.:.....:
  Rat   818 GEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIEKV--MISSNAEDAFL 880

  Fly   858 VAITLRVPRPATIGDKFASRAGQKGICSQKYPAEDLPFTESGLIPDIVFNPHGFPSRMTIAMMIE 922
            :.:.||..|...|||||:||.||||:|....|.||:||.:||:.|||:.||||||||||:..:||
  Rat   881 IKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIE 945

  Fly   923 TMAGKGAAIHGNVYDATPFRFSEENTAIDYFGKMLEAGGYNYYGTERLYSGVDGREMTADIFFGV 987
            .:|||...:.|..:..|.|..|:.....:    .|...||||.|.:.:.||:.|..:.|.|:||.
  Rat   946 LLAGKAGVLDGRFHYGTAFGGSKVKDVCE----DLVRHGYNYLGKDYVTSGITGEPLEAYIYFGP 1006

  Fly   988 VHYQRLRHMVFDKWQVRSTGAVEARTHQPIKGRKRGGGVRFGEMERDALISHGAAFLLQDRLFHN 1052
            |:||:|:|||.||...|:.|.....|.||.:||.|.||:|.||||||.||.:||:.||.:||..:
  Rat  1007 VYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMIS 1071

  Fly  1053 SDKTHTLVCHKCGSILAPLQRIVKRNETGGLSSQPDTCRLCGDNSSVSMIEIPFSFKYLVTELSS 1117
            ||.....||.:||.:              |.|.   .|..|..:..||.:.||::.|.|..||.|
  Rat  1072 SDAFEVDVCGQCGLL--------------GYSG---WCHYCKSSCHVSSLRIPYACKLLFQELQS 1119

  Fly  1118 VNINARFKL 1126
            :||..|.||
  Rat  1120 MNIIPRLKL 1128

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RpI135	NP_476708.1	RpoB	34..1128	CDD:223163	343/1179 (29%)
		RNA_pol_B_RPB2	35..1125	CDD:238353	341/1176 (29%)
		RNA_pol_Rpa2_4	564..614	CDD:284335	11/49 (22%)
Polr3b	NP_001178807.1	PRK08565	26..1129	CDD:236291	343/1179 (29%)
		RNA_pol_B_RPB2	39..1127	CDD:238353	341/1176 (29%)
		RNA_pol_Rpb2_4	539..600	CDD:282431	18/67 (27%)
		RNA_pol_Rpb2_5	621..661	CDD:282432	12/40 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0085
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D42570at2759
OrthoFinder	1	1.000	-	-		FOG0000346
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820