Protein Alignment RpI135 and polr2b

DIOPT Version :9

• Sequence 1: NP_476708.1
• Gene: RpI135 / 33210
• FlyBaseID: FBgn0003278
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: XP_002937598.2
• Gene: polr2b / 100380205
• XenbaseID: XB-GENE-1012874
• Length: 1174
• Species: Xenopus tropicalis
• Alignment Length: 1222
• Identity: 332/1222 - (27%)
• Similarity: 540/1222 - (44%)
• Gaps: 233/1222 - (19%)

  Fly    40 VDSFDEMLTVGLDNSAKHMIP-------NHWLSPAGE--KISMKVESIWIAKPK------VPQDV 89
            :|||||.:.:.:....:...|       .|......|  :..:|.|.|:::||.      .|..:
 Frog    44 LDSFDEFIQMSVQRIVEDAPPIDLQAEAQHTTGEVEEPPRYLLKFEQIYLSKPTHWERDGAPSPM 108

  Fly    90 IDVRTREIYPTDSRQLHVSYSGMCSVRLGWSV-----NGVQKTPINMDLGEVPIMLRSKACNLGQ 149
            :        |.::|..:::||....|.:..:|     ..:|.......:|::||||||..|.|..
 Frog   109 M--------PNEARLRNLTYSAPLYVDITKTVVKEGEEQIQTQHQKTFIGKIPIMLRSTYCLLNG 165

  Fly   150 ATPEEMVKHGEHDSEWGGIFVIRGNEK--IVRMLIMTRRNHPICVKRSSWKDRGQNFSDLGMLVQ 212
            .|..::.:..|...:.||.|:|.|:||  |.:..:.|...:....|.|.:....:..|   .|..
 Frog   166 LTDRDLCELNECPLDPGGYFIINGSEKVLIAQEKMATNTVYVFAKKDSKYAYTAECRS---CLEN 227

  Fly   213 TVREDESSLSNVVHYLNNGTAKFMFSH--VKRLSY----VPVCLILKCLMDYTDEEIYNRLVQGY 271
            :.|...|...:::.....|..|.....  |..|.|    ||:.::.:.|...:|.:|...::..:
 Frog   228 SSRPTSSIWVSMLARGGQGAKKSAIGQRIVATLPYIKQEVPIIIVFRALGFVSDRDILEHIIYDF 292

  Fly   272 ESDQYYVSCVQAMLRE---VQNENVYTHAQCKSFIGNLFRARFPEVPEWQPDDDVTDFILRERVM 333
            | |...:..|:..|.|   :|.:||     ..:|||:  |...|.|.: :........:|::.::
 Frog   293 E-DPEMMEMVKPSLDEAFVIQEQNV-----ALNFIGS--RGAKPGVTK-EKRIKYAKEVLQKEML 348

  Fly   334 IHLDTYE----DKFQLIVFMIQKLFQCAQGKYKVENVDSAMMQEVLLPGHLYQKYLSERVESWVS 394
            .|:...:    .|...:.:|:.:|...|.|:.::::.|....:.:.|.|.|.........::.:.
 Frog   349 PHVGVSDFCETKKAYFLGYMVHRLLLAALGRRELDDRDHYGNKRLDLAGPLLAFLFRGMFKNLLK 413

  Fly   395 QVRRCLQKKL-TSPDALVTSAVMTQCMRQAGGVGRAIESFLATGNIA-------SRTGLGLMQNS 451
            :||...||.: ...|..:..|:.|:.      :...::..|||||..       :|.|
 Frog   414 EVRIYAQKFIDRGKDFNLELAIKTRI------ISDGLKYSLATGNWGDQKKAHQARAG------- 465

  Fly   452 GLVIMAENINRMRY---MSHFRAIH----RGSYFTTMRTTEARQLLPDAWGFICPVHTPDGTPCG 509
                :::.:||:.:   :||.|.::    |..     :..:.|||....||.:||..||:|...|
 Frog   466 ----VSQVLNRLTFASTLSHLRRLNSPIGRDG-----KLAKPRQLHNTLWGMVCPAETPEGHAVG 521

  Fly   510 LLNHLTLTCEISM--RPDP-----------KLVKAIPKHLIDMGMMPLSNRRYLGEKLYVVFLDG 561
            |:.:|.|...||:  :|.|           .|.:..|..:.|...               :|::|
 Frog   522 LVKNLALMAYISVGSQPSPILEFLEEWSMENLEEISPAAIADATK---------------IFVNG 571

  Fly   562 KHLGHIHQSEAEKIVDELRYGKIFGTLPQMMEI--GFIPFKKNGQFPGLYIATGPARMMRPVW-- 622
            ..:| ||: :.|::::.||      .|.:.|:|  ..:...::.:...:.|.|...|:.||:.
 Frog   572 CWVG-IHK-DPEQLMNTLR------KLRRQMDIIVSEVSMIRDIREREIRIYTDAGRICRPLLIV 628

  Fly   623 ---------------------NLKWKR------VEYIGTLEQLYMEIAIDAKEM------YPDFT 654
                                 |..|:.      ||||.|||:..:.:|:...::      |....
 Frog   629 EKQKLLLKRRHIDQLKEREYNNYSWQDLVASGVVEYIDTLEEETVMLAMTPDDLQEKGVAYCSTY 693

  Fly   655 THLELAKTHFMSNLANLIPMPDYNQSPRNMYQCQMGKQTMGTPCLNWPKQAANKLYRLQTPGTPL 719
            ||.|:..:..:...|::||.||:||||||.||..||||.||....|:..:.....:.|..|..||
 Frog   694 THCEIHPSMILGVCASIIPFPDHNQSPRNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPQKPL 758

  Fly   720 FRPVHYDNIQLDDFAMGTNAIVAVISYTGYDMEDAMIINKAAYERGFAYGSIYKTKFLTLDKKSS 784
            ......:.::..:...|.|:|||:.|||||:.||::|:|::|.:||| :.|::...:...:.|..
 Frog   759 VTTRSMEYLRFRELPAGINSIVAIASYTGYNQEDSVIMNRSAVDRGF-FRSVFYRSYKEQESKKG 822

  Fly   785 Y---------------FARHPHMPELIKHLDTDGLPHPGSKLSYGSPLYCYFDGEVATYKVVKMD 834
            :               ..||    .:...||.|||..||.::|         ..:|...|.|.:.
 Frog   823 FDQEEVFEKPTRETCQGMRH----AIYDKLDDDGLIAPGVRVS---------GDDVIIGKTVTLP 874

  Fly   835 EKEDCIVESIRQLGSFDLSP---------------------KKMVAITLRVPRPATIGDKFASRA 878
            |.||.:..:.|:....|.|.                     .|...|.:|..|...||||||||.
 Frog   875 ENEDELESTNRRYTKRDCSTFLRTSETGIVDQVMVTLNQEGYKFCKIRVRSVRIPQIGDKFASRH 939

  Fly   879 GQKGICSQKYPAEDLPFTESGLIPDIVFNPHGFPSRMTIAMMIETMAGKGAAIHGNVYDATPFRF 943
            ||||.|..:|..||:|||..|:.|||:.|||..|||||:..:||.:.||.:|..|.:.|||||
 Frog   940 GQKGTCGIQYRQEDMPFTCEGITPDIIINPHAIPSRMTVGHLIECLQGKVSANKGEIGDATPF-- 1002

  Fly   944 SEENTAIDY--FGKMLEAGGYNYYGTERLYSGVDGREMTADIFFGVVHYQRLRHMVFDKWQVRST 1006
               |.|::.  ...:|...||:..|.|.||:|..||::|:.||.|..:||||:|||.||...|:.
 Frog  1003 ---NDAVNVQKISNLLSDYGYHLRGNEVLYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHSRAR 1064

  Fly  1007 GAVEARTHQPIKGRKRGGGVRFGEMERDALISHGAAFLLQDRLFHNSDKTHTLVCHKCGSILAPL 1071
            |.::....||::||.|.||:||||||||..|:||||..|::|||..||.....||:.||.:....
 Frog  1065 GPIQILNRQPMEGRSRDGGLRFGEMERDCQIAHGAAQFLRERLFEASDPYQVHVCNLCGLMAIAN 1129

  Fly  1072 QRIVKRNETGGLSSQPDTCRLCGDNSSVSMIEIPFSFKYLVTELSSVNINAR 1123
            .|           :....||.|.:.:.:|::.:|::.|.|..||.|::|..|
 Frog  1130 TR-----------THTYECRGCRNKTQISLVRMPYACKLLFQELMSMSIAPR 1170

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RpI135	NP_476708.1	RpoB	34..1128	CDD:223163	332/1222 (27%)
		RNA_pol_B_RPB2	35..1125	CDD:238353	332/1222 (27%)
		RNA_pol_Rpa2_4	564..614	CDD:284335	11/51 (22%)
polr2b	XP_002937598.2	PRK08565	27..1172	CDD:236291	332/1222 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D42570at2759
OrthoFinder	1	1.000	-	-		FOG0000346
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920