Protein Alignment CG4213 and LOC1278098

DIOPT Version :10

• Sequence 1: NP_608520.1
• Gene: CG4213 / 33209
• FlyBaseID: FBgn0031251
• Length: 1253
• Species: Drosophila melanogaster
• Sequence 2: XP_061516383.1
• Gene: LOC1278098 / 1278098
• VectorBaseID: AGAMI1_005167
• Length: 1267
• Species: Anopheles gambiae
• Alignment Length: 1383
• Identity: 423/1383 - (30%)
• Similarity: 607/1383 - (43%)
• Gaps: 411/1383 - (29%)

  Fly     1 MGNAESTQSADDTQMQMQQS---------------------TDDEPWWNNIEHEDLILEQAPRAT 44
            ||..:|.....:||...::|                     ||||      .|:..|..|
Mosquito     1 MGGVQSANDGRETQTSDRESSHMSNHTPPSVPVPDSVAALKTDDE------LHDATIPPQ----- 54

  Fly    45 TQKEAEEVLPENRVKYRENKVAIEMEDKGNETHQ-REQTLE--EFREELRQKKEVRQNAVQGLRD 106
            .|.:.|.|..:.:....::..|.|.:|...|..| |:.|:|  .||.:|:||:::.|:.:..::|
Mosquito    55 EQDDPEPVGDDAQRSAHDSDAAAESDDSMTEECQARKMTVELANFRRDLQQKRQLHQSKLVAVKD 119

  Fly   107 EIASLKEQLAIEKSENQRLRKVT----------ATDGQA-------------------------- 135
            |:..|::.||.||..|:.|.|..          |.||:.
Mosquito   120 ELEHLRKALAEEKRRNRALIKYVQQQELQLTKHANDGEGAEETPACGAVRREALQIVASGENAPL 184

  Fly   136 ------------DNQHDHSNSPSKPDADPDD---------------------------------- 154
                        |.:||.|:|......:..|
Mosquito   185 EPAERVNAEAAEDERHDQSSSAGGQSVERADGERLALKRELAESQHALQCTTGELLELRHELAQL 249

  Fly   155 -----------ENPSSR----SRHANIELANAQLALQQAQAENLSLRGEVEVVQRQVGTLKEVIS 204
                       |..|||    :|....|||..|..||.:|||.|||:.:|:.::.||.:||:||.
Mosquito   250 RTQLRAQQDEAEAESSRQCGAARTLKAELAETQFRLQISQAEALSLQTDVDQLRNQVKSLKDVIK 314

  Fly   205 CCKQMLSVKEEQCAQLKMKLTEIENSFSEREMKIMSNNLRQEYERQLVNIRQLRQLYEERQRVAA 269
            ..|::::::|:|..|||.||.:||::..|||::|||::||:||:|||.|||.||.|||||:||:.
Mosquito   315 AGKEIIAIREDQVEQLKGKLRQIEDTLQERELQIMSDDLRREYDRQLTNIRNLRDLYEERERVSR 379

  Fly   270 AEYENLQRLISIKRDELTAEQDKNKSLEDRNHSLLKEVEMANEELAKLREECGEHKFEKRLLSEQ 334
            .|.:||.|.:.:|::||..||:|||:||....||..::.....||.:.:::..:.:.|.:.|..:
Mosquito   380 MERDNLVRQLDLKKNELATEQEKNKNLEALVESLQTDLTRLRTELEQTQDKLAQSQAESKQLQLE 444

  Fly   335 VGAVNMLFSQLIMGFNGK---SSMNIDRVNRMLEENRHLLNQMTQAEGNCSD-GATLPKLLFDLV 395
            :|.||...|:.::|.:.|   |.:|||::..:|||||.||.:||:.|....| ||.||:.|:||:
Mosquito   445 MGVVNQFISKFLLGMSRKPTASDINIDKLAAVLEENRDLLIEMTKDEAETIDTGAFLPRALYDLI 509

  Fly   396 EQATGHGDSAEESDKSRSATPTPKATPTKEDTTDGCQPGGE-----VEKCRKGSSRSGSGVDATA 455
            .:.    |.|.|         .|.....||:  ||.:..||     |:|
Mosquito   510 TEV----DEANE---------LPPGNDGKEE--DGAEASGEDEFTDVQK---------------- 543

  Fly   456 ASLKSHEPEIMGKVASAQEIIGNLPKVWKVLMELLSHHKIERVQLEELPSSSAAFPSSSASNASG 520
                          ||.::|...|||||:||:||::|.  ||.|       ...|.....|....
Mosquito   544 --------------ASPEQIADKLPKVWRVLIELVNHQ--ERAQ-------PVPFVEGGESEECL 585

  Fly   521 KDEGESHRKPPELSVSKTYIKLKDLILEKKSLVKETTRLKTLNSHLDYRLNQQEKRLSGVSLELT 585
            |.....:.....:|||||||||||||||||||.|||.||:||||||:.||:.||||||.||||||
Mosquito   586 KSVQTRNGPKTVVSVSKTYIKLKDLILEKKSLKKETNRLRTLNSHLERRLDSQEKRLSAVSLELT 650

  Fly   586 KTWHLVGKMQRQHRQLHTQEQILRYQLQQKRRLLSELKDELEYCRRKWALARAKNDESQEQCDEW 650
            |||||||||||||||||||||||||.||||||||||||:||||||.||:.||.||.||:.|....
Mosquito   651 KTWHLVGKMQRQHRQLHTQEQILRYHLQQKRRLLSELKEELEYCRLKWSAAREKNIESEGQWKSL 715

  Fly   651 RREF-ARRKLEDANHSAESGYSDSGPQSDE----------------------------------- 679
            :.:| ||||.:..|:|.||||||..|..:|
Mosquito   716 KADFAARRKQDSLNNSGESGYSDEQPSDEEDTHVNRKSSLANQQSPGFSGGATTGLESDKWSQMV 780

  Fly   680 -----------------------------ERDLGTVDPVEAPTSSSTCRRKLLRD----QFEH-- 709
                                         |.|:.:::.||  .::..|..| :.|    .||.
Mosquito   781 GRLDKCFVGSSLSNIYHLAVASVLRKVHSESDMKSLENVE--RANQFCNEK-IEDLPIFPFEEDE 842

  Fly   710 ------------TRKIKRMQSTSPG--RQGFEGEEAEADNIVLR-WNSAPPTCGWREEAEEGEDV 759
                        .|| ||..::..|  |....|:...|.::.|| .|.|   .|.::|.:|.|:.
Mosquito   843 PGPEEPEEIPVVLRK-KRRSASKKGKKRHNDAGQPESAQDMFLRLMNLA---AGGQDEVDEDEED 903

  Fly   760 DELEEEGAHGLLPKSLHSSRSRQRSVEGSSETAG------TASRIQKLEEQCKNL--IQQVLETS 816
            |:.:|:              ..:|:..|:.:..|      :||.:.:.|.:|..:  :.:..|:|
Mosquito   904 DDADEQ--------------DFERTGTGNDDAEGEYSENESASELSEEELECLEMAVMDERAESS 954

  Fly   817 GNRERLEIQLCQFQDDIAPAQHAVPLEEFINRKRMERMTR-------------------ASSAPA 862
            ..:||||........|   |...:..||...|||..|:.|                   ||.||.
Mosquito   955 VTQERLEGPDASSHSD---ADRELSSEELFQRKREARLQRMAELNSRLDRYSSPTPTASASEAPV 1016

  Fly   863 ------TGS-----------LTPREEEYTRKRSERLGRLEEESRQLMSRIRRTADRGHYLKKSLD 910
                  ||.           |:..|::|.::|:|||.|||.|:::..||:.:|..||..:...:|
Mosquito  1017 QTESGETGETSQSKTDEQVVLSEDEQKYLQRRAERLERLEREAKEFRSRLSKTVHRGTEISAQID 1081

  Fly   911 RIRRAPSREASFESNTEEEAIPASKSE--------SCPATSPLTAEEEEYTSRRAARIQRMERES 967
            .|     ........|:...:|....|        ||     ||.:|.||||.||.|::|:|.||
Mosquito  1082 EI-----HNGFMARQTDSSPVPGCSGEAQSSRVDLSC-----LTDKEREYTSARAERLERLESES 1136

  Fly   968 RQLISQLTRNSERGENFATKLDTLHEQYGPNPQLDQDRSSTSMSQTLEQRLEDIERVSATRAERL 1032
            ::|:.|:.:...||.:..||||.||.:|| :|..::..::...|...||:..:
Mosquito  1137 QKLLKQMNQTMRRGSSLTTKLDMLHTRYG-SPAANEPEANVETSARPEQQTAN------------ 1188

  Fly  1033 RILELQGNELIARLSSTSERGTAMINRIAEREATRRQEAE--------------LVEQTVSSEEA 1083
                  |:||       ....|.......|.|....||.|              .:|..:.|:|.
Mosquito  1189 ------GDEL-------GPEETPKPEPAVETEENVPQEQEEQDYAVGGPYVPMGPIELVLVSDEE 1240

  Fly  1084 TSSEASTRIVRHPEEEAE 1101
            ...|.|..:    |||.:
Mosquito  1241 VMDEVSNLL----EEETQ 1254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4213	NP_608520.1	SMC_prok_B	<62..335	CDD:274008	112/372 (30%)
LOC1278098	XP_061516383.1	None