Protein Alignment al and crx

DIOPT Version :10

• Sequence 1: NP_722629.1
• Gene: al / 33208
• FlyBaseID: FBgn0000061
• Length: 408
• Species: Drosophila melanogaster
• Sequence 2: NP_694419.1
• Gene: crx / 81881
• ZFINID: ZDB-GENE-010403-1
• Length: 281
• Species: Danio rerio
• Alignment Length: 285
• Identity: 83/285 - (29%)
• Similarity: 116/285 - (40%)
• Gaps: 95/285 - (33%)

  Fly    80 APKRKQRRYRTTFTSFQLEELEKAFSRTHYPDVFTREELAMKIGLTEARIQVWFQNRRAKWRKQE 144
            |..|||||.|||||..||:.||..|::|.|||:|.|||:|:||.|.|:|:||||:|||||.|:|:
Zfish    33 ATPRKQRRERTTFTRTQLDILEALFTKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQ 97

  Fly   145 KV---GPQSHPYN------PYLPGGAATMQTVVGAALPPNPFTHLGFQLRKPFDAQHAANLAAFR 200
            :.   .|:..|..      |.|.....|..:||.|..|..|
Zfish    98 QQTSGQPKPRPPKKKSSPPPDLTSDPGTSSSVVAAPTPTVP------------------------ 138

  Fly   201 YPHLSAAPMIPSGYFNQFQRAPPHMLPHGMAGMYSPSSSFQSLLANMTAVP-----RGTPLGKPP 260
                   |.:.:|      .||        ..::||:|        ::.:|     .|||..:.|
Zfish   139 -------PSVSAG------TAP--------VSVWSPTS--------LSPLPDPLCGSGTPCVQRP 174

  Fly   261 ALLVGSPDLHSPNHMLASPPTSPASGHASQHQQHPTAHPPPPQAPPQMPVGVQPAQLSPQHLVGI 325
            |          |..|....|:|.:.|:.|              :|....:...| .|||   :..
Zfish   175 A----------PYPMSYGQPSSYSQGYGS--------------SPYFSGLDCSP-YLSP---MTT 211

  Fly   326 ALTQQASSLSPTQTSPVALTLSHSP 350
            .|:....:|||.....:..:||.||
Zfish   212 QLSASGGALSPLTVPSMGGSLSQSP 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeodomain	86..142	CDD:459649	35/55 (64%)
		OAR	374..391	CDD:461067
crx	NP_694419.1	homeodomain	38..97		37/58 (64%)
		Homeodomain	49..94	CDD:459649	28/44 (64%)
		TF_Otx	152..230	CDD:427350	24/113 (21%)