DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment al and Rhox13

DIOPT Version :9

Sequence 1:	NP_722629.1	Gene:	al / 33208	FlyBaseID:	FBgn0000061	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001171931.1	Gene:	Rhox13 / 73614	MGIID:	1920864	Length:	232	Species:	Mus musculus

Alignment Length:	195	Identity:	53/195 - (27%)
Similarity:	72/195 - (36%)	Gaps:	63/195 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 EELPQEAKLAHPDAVVLVDRAPGSSAASAGAALTVSMSVSGGAPSGASGASGGTNSPVSDGNSDC 74
            ||...||: |...|....:.|||  |.....|...|...|||| .|.:......:...|:.:|:.
Mouse    18 EETNAEAQ-AGAMAATSTEEAPG--AVEVAQAAVASSHDSGGA-IGCATVKESESDSESESDSES 78

  Fly    75 EAD------------------------------------------------------EYAPKRKQ 85
            |:|                                                      .|.|.|:.
Mouse    79 ESDSSDSSDESDDDSSTSDEDTSDPEEAAAPSVAAVAAAAAPPTVPAAAAIQIPGPYRYRPPRRH 143

  Fly    86 RRYRTT-----FTSFQLEELEKAFSRTHYPDVFTREELAMKIGLTEARIQVWFQNRRAKWRKQEK 145
            .|.|..     |..:|:||:|..|..|.|||:.||.|||..:.:.|.:::|||.|||||.||.|:
Mouse   144 VRRRRRGPPFHFAQWQVEEMESLFEETQYPDLLTRGELARTLNVPEVKVKVWFTNRRAKQRKIER 208

Fly 146 145
Mouse 209 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeobox	89..141	CDD:278475	25/56 (45%)
al	NP_722629.1	OAR	374..391	CDD:281777
Rhox13	NP_001171931.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	45..114		11/69 (16%)
Rhox13	NP_001171931.1	Homeobox	155..204	CDD:278475	24/48 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000