Protein Alignment al and RHOXF2B

DIOPT Version :10

• Sequence 1: NP_722629.1
• Gene: al / 33208
• FlyBaseID: FBgn0000061
• Length: 408
• Species: Drosophila melanogaster
• Sequence 2: NP_001093155.1
• Gene: RHOXF2B / 727940
• HGNCID: 33519
• Length: 288
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 69/256 - (26%)
• Similarity: 102/256 - (39%)
• Gaps: 63/256 - (24%)

  Fly     1 MGISEEIKLEELPQEAKLAHPDAVVLVDRAPGSSAASAGAALTVSMSVSGG---------APSGA 56
            :.::||:|.||   |.....|:.    ..|.|....||||        .||         ...|.
Human    33 LSLTEEVKEEE---EDAQPEPEQ----GTAAGEKLKSAGA--------QGGEEKDGGGEEKDGGG 82

  Fly    57 SGASG--------GTNSPVSDGN-SDCEADEYAPKRKQRRYR----------------TTFTSFQ 96
            :|..|        ||:.  |||| .|.:..|..|.::..|.:                ..||..|
Human    83 AGVPGHLWEGNLEGTSG--SDGNVEDSDQSEKEPGQQYSRPQGAVGGLEPGNAQQPNVHAFTPLQ 145

  Fly    97 LEELEKAFSRTHYPDVFTREELAMKIGLTEARIQVWFQNRRAKWRKQEKVGPQSHPYNPYLPGGA 161
            |:|||..|.|..:|..|.|..||..:.:||..:|:||:|||||||:.:: ...:....|::..|.
Human   146 LQELECIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQR-ALMARNMLPFMAVGQ 209

  Fly   162 ATMQTVVGAALPPNPFTHLGFQLRKPFDAQHAANLA---------AFRYPHLSAAPMIPSG 213
            ..|.|...|...|...:  |.:....:|..|:::|.         :...|.:...||.|:|
Human   210 PVMVTAAEAITAPLFIS--GMRDDYFWDHSHSSSLCFPMPPFPPPSLPLPLMLLPPMPPAG 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeodomain	86..142	CDD:459649	26/71 (37%)
		OAR	374..391	CDD:461067
RHOXF2B	NP_001093155.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..136		28/119 (24%)
		Homeodomain	139..191	CDD:459649	25/51 (49%)
		PRK02287	<183..>232	CDD:235024	14/51 (27%)
		Nuclear localization signal. /evidence=ECO:0000250	186..195		5/9 (56%)