DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment al and Isx

DIOPT Version :9

Sequence 1:	NP_722629.1	Gene:	al / 33208	FlyBaseID:	FBgn0000061	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001281207.1	Gene:	Isx / 71597	MGIID:	1918847	Length:	242	Species:	Mus musculus

Alignment Length:	265	Identity:	82/265 - (30%)
Similarity:	105/265 - (39%)	Gaps:	109/265 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 KRKQRRYRTTFTSFQLEELEKAFSRTHYPDVFTREELAMKIGLTEARIQVWFQNRRAKWRKQEKV 146
            |:.:||.|||||:.||:||||.|..|||||:..|.:||.:|.|.|||:|:||||:|||||||||.
Mouse    75 KKNKRRVRTTFTTEQLQELEKLFHFTHYPDIHVRSQLASRINLPEARVQIWFQNQRAKWRKQEKS 139

  Fly   147 GPQSHPYNPYLPGGAATMQTVVGAALPPNPFTHLGFQLRKPFDAQHAANLAAFRYPHLSAAPMIP 211
            |..|.|..   ||..|.              ||.                    |.::..:
Mouse   140 GNLSAPQQ---PGSCAD--------------THC--------------------YDYIGTS---- 163

  Fly   212 SGYFNQFQRAPPHMLPHGMAGMYSPSSSFQSLLANMTAVPRGTPLGKPPALLVGSPDLHSPNHML 276
                            |.|....|.|:.|:.:                       |...||..|.
Mouse   164 ----------------HRMLPTLSDSAPFKLV-----------------------PYTDSPCPMA 189

  Fly   277 ASPPTSPASGHASQHQQHPTA-----HPPPPQAPPQMPVGVQPAQLSPQHL----VG--IALTQQ 330
            ...||:||      ...||.:     |.|.|  .||  ||        |||    :|  .:|::|
Mouse   190 PMGPTAPA------WPSHPASLCPYLHVPTP--TPQ--VG--------QHLCNFNIGTDFSLSKQ 236

  Fly   331 ASSLS 335
            |:.||
Mouse   237 ATLLS 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeobox	89..141	CDD:278475	33/51 (65%)
al	NP_722629.1	OAR	374..391	CDD:281777
Isx	NP_001281207.1	Homeobox	82..134	CDD:278475	33/51 (65%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24329
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010