DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment al and pax5

DIOPT Version :9

Sequence 1:	NP_722629.1	Gene:	al / 33208	FlyBaseID:	FBgn0000061	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	XP_005170979.1	Gene:	pax5 / 60636	ZFINID:	ZDB-GENE-001030-2	Length:	423	Species:	Danio rerio

Alignment Length:	314	Identity:	77/314 - (24%)
Similarity:	125/314 - (39%)	Gaps:	59/314 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KLEELPQE--AKLAHPDA-VVLVDRAPGSSAASAGAALTVSMSVSGGAPSGASGASGG---TNSP 66
            |:::.|.:  |..||..| .|.|.:....::.:||::.::|..:...:|:.||.....   .:||
Zfish   142 KVQQPPGQSGAVSAHNLASTVAVTQVSAVTSDAAGSSYSISGILGISSPADASKRKRDDPLQDSP 206

  Fly    67 VSDGNSDCEADEYAPKRKQRRYRTTFTSFQLEELEKAFSRTHYPDVF------------TREELA 119
            :::|:|....|..   |||.| ...||..|||.|:..|.|..:||::            |.:..|
Zfish   207 LANGHSHSGRDFL---RKQMR-GELFTPQQLEVLDHVFDRQPFPDIYPIPDSISYKPSQTTDYSA 267

  Fly   120 MKI---GLTEARIQVWFQNRRAKWRKQEKVGPQSHPYNPYLPGGAATMQTVVGAALPPNPFTHLG 181
            |..   ||.|.:..:  .|:..........||||:|    |..|.....|.:....|..|.|..|
Zfish   268 MASLAGGLEEMKNSL--ANQTGAELGSTVAGPQSYP----LVSGRDLASTTLPGYPPHVPPTGQG 326

  Fly   182 FQLRKPFDAQHAANLAAFRYPHLSAAPMIPSGYFNQFQRAPPHMLPHGMAGMY-SPS-----SSF 240
                            ::..|.|:.  |:|.|.|:....:.|....:..:..: :||     ..:
Zfish   327 ----------------SYSTPSLTG--MVPGGDFSGSPYSHPQYSTYNESWRFANPSLLVFQQEY 373

  Fly   241 QSLLANMTAVPRGTPLGKPPALLVGSPDLHSPNHMLASPPTSPASGHASQHQQH 294
            .|||.:..|...|...|:.|. ..|||..:|.....|.   :.|:..||.:.:|
Zfish   374 GSLLGSERAASSGLFPGQTPQ-PTGSPYYYSAATRGAG---TAATATASAYDRH 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeobox	89..141	CDD:278475	17/66 (26%)
al	NP_722629.1	OAR	374..391	CDD:281777
pax5	XP_005170979.1	PAX	16..140	CDD:128645
pax5	XP_005170979.1	Pax2_C	280..403	CDD:289189	32/147 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910