Protein Alignment al and ALX4

DIOPT Version :9

• Sequence 1: NP_722629.1
• Gene: al / 33208
• FlyBaseID: FBgn0000061
• Length: 408
• Species: Drosophila melanogaster
• Sequence 2: NP_068745.2
• Gene: ALX4 / 60529
• HGNCID: 450
• Length: 411
• Species: Homo sapiens
• Alignment Length: 397
• Identity: 119/397 - (29%)
• Similarity: 151/397 - (38%)
• Gaps: 146/397 - (36%)

  Fly     2 GISEEIKLEELPQEAKLAHPDAVVLVDRAPGSSAASAGAALTVSMSVSGGAPSGASGASGGTNSP 66
            |.|..:::....:|:.|..|:.      .|.|.        ||.|.     .|..|....|...|
Human   145 GHSAALQVPCYAKESSLGEPEL------PPDSD--------TVGMD-----SSYLSVKEAGVKGP 190

  Fly    67 VSDGNSDC-----EADEYAPKRKQRRYRTTFTSFQLEELEKAFSRTHYPDVFTREELAMKIGLTE 126
            ....:||.     :||..:.|.|:||.||||||:|||||||.|.:||||||:.||:|||:..|||
Human   191 QDRASSDLPSPLEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTE 255

  Fly   127 ARIQVWFQNRRAKWRKQEKVGPQSHPYNPYLPGGAATMQTVVGAALPPNPFTHLGFQLRKPFDAQ 191
            ||:|||||||||||||:|:.|               .||                 |:|..|.
Human   256 ARVQVWFQNRRAKWRKRERFG---------------QMQ-----------------QVRTHFS-- 286

  Fly   192 HAANLAAFRYPHLSAAPMIPSGYFNQFQRAPPHMLPHGMAGMYSPSSSFQSLLANMTAVPRGTPL 256
                 .|:..|.|:.|.       |..|...|..|  |..|..||
Human   287 -----TAYELPLLTRAE-------NYAQIQNPSWL--GNNGAASP-------------------- 317

  Fly   257 GKPPALLVGSPDLHSPNHMLASPPTSPASGHASQHQQHPTAHPPPPQAPPQ---MPVGVQPAQLS 318
              .||.:|               |..|.....|.|     ||||...|...   :.|....:.:.
Human   318 --VPACVV---------------PCDPVPACMSPH-----AHPPGSGASSVTDFLSVSGAGSHVG 360

  Fly   319 PQHLVGIALTQQASSLSPTQTSPVALTLSHSPQRQLPPPSHQAPPPPPRAATPPEDRRTSSIAAL 383
            ..|:..:.   .|:||||...   ...|:..|                       ||:|||||||
Human   361 QTHMGSLF---GAASLSPGLN---GYELNGEP-----------------------DRKTSSIAAL 396

  Fly   384 RLKAREH 390
            |:||:||
Human   397 RMKAKEH 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeobox	89..141	CDD:278475	40/51 (78%)
		OAR	374..391	CDD:281777	14/17 (82%)
ALX4	NP_068745.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..145		119/397 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	184..219		10/34 (29%)
		Homeobox	218..270	CDD:278475	40/51 (78%)
		OAR	387..404	CDD:281777	14/17 (82%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	391..404		11/13 (85%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	147	1.000	Inparanoid score	I4418
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D454642at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24329
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.070