Protein Alignment al and PRRX1

DIOPT Version :10

• Sequence 1: NP_722629.1
• Gene: al / 33208
• FlyBaseID: FBgn0000061
• Length: 408
• Species: Drosophila melanogaster
• Sequence 2: NP_073207.1
• Gene: PRRX1 / 5396
• HGNCID: 9142
• Length: 245
• Species: Homo sapiens
• Alignment Length: 191
• Identity: 69/191 - (36%)
• Similarity: 94/191 - (49%)
• Gaps: 28/191 - (14%)

  Fly     3 ISEEIKLEELPQEAKLAHPDAVVLVDRAPGSSAASAGAALTVSMSVSGGAPSGASGASGGTNSPV 67
            :|..:.|||           |..:|......:...||.:|..|           .|.:.|:::|.
Human    36 VSHLLDLEE-----------AGDMVAAQADENVGEAGRSLLES-----------PGLTSGSDTPQ 78

  Fly    68 SDGNSDCEADEYAPKRKQRRYRTTFTSFQLEELEKAFSRTHYPDVFTREELAMKIGLTEARIQVW 132
            .| |....::| ..||||||.||||.|.||:.||:.|.||||||.|.||:||.::.|||||:|||
Human    79 QD-NDQLNSEE-KKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVW 141

  Fly   133 FQNRRAKWRKQEK---VGPQSHPYNPYLPGGAATMQTVVGAALPPNPFTHLGFQLRKPFDA 190
            |||||||:|:.|:   ....:.....|.....|..|.:|... .|.|..:|.:....|:.|
Human   142 FQNRRAKFRRNERAMLANKNASLLKSYSGDVTAVEQPIVPRP-APRPTDYLSWGTASPYSA 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeodomain	86..142	CDD:459649	38/55 (69%)
		OAR	374..391	CDD:461067
PRRX1	NP_073207.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..103		18/52 (35%)
		Homeodomain	99..151	CDD:459649	35/51 (69%)
		OAR	219..235	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	222..235