Protein Alignment al and PAX3

DIOPT Version :9

• Sequence 1: NP_722629.1
• Gene: al / 33208
• FlyBaseID: FBgn0000061
• Length: 408
• Species: Drosophila melanogaster
• Sequence 2: NP_852124.1
• Gene: PAX3 / 5077
• HGNCID: 8617
• Length: 505
• Species: Homo sapiens
• Alignment Length: 384
• Identity: 111/384 - (28%)
• Similarity: 150/384 - (39%)
• Gaps: 118/384 - (30%)

  Fly     2 GISEEIKLEEL---PQEAKLAHPDAVVLVDRAPGSSAASAGAALTVSMSVSGGAPSGASGASGGT 63
            |..||..||..   ..|.|..|....:|.:||
Human   165 GEEEEADLERKEAEESEKKAKHSIDGILSERA--------------------------------- 196

  Fly    64 NSPVSDGNSDCEADEYAP-KRKQRRYRTTFTSFQLEELEKAFSRTHYPDVFTREELAMKIGLTEA 127
            ::|.||..||.:::...| ||||||.|||||:.||||||:||.||||||::||||||.:..||||
Human   197 SAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEA 261

  Fly   128 RIQVWFQNRRAKWRKQEKVGPQSHPYNPYLPGGAATMQTVVGAALPPNPFTHLGFQLRKPFDAQH 192
            |:||||.||||:||||.... |...:|..:|||           .||
Human   262 RVQVWFSNRRARWRKQAGAN-QLMAFNHLIPGG-----------FPP------------------ 296

  Fly   193 AANLAAFRYPHLSAAPMIPSGYFNQFQRAPPHMLPHGMAGMYSPSSSFQSLLANMTAVPRGTPLG 257
                        :|.|.:|:...::..              |.|:|..|::....:.|.|..||
Human   297 ------------TAMPTLPTYQLSETS--------------YQPTSIPQAVSDPSSTVHRPQPL- 334

  Fly   258 KPPALLVGSPDLHSPNHMLASPPTSPASGHASQHQQHPTAHPPPPQAPPQMPVGVQPAQLSPQHL 322
             ||:.:..|....:|:.  :|....|::.|...........|..|..|....:|   ..|||| :
Human   335 -PPSTVHQSTIPSNPDS--SSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIG---NGLSPQ-V 392

  Fly   323 VGI---------------ALTQQASSLSPTQTSPVALT--LSHSPQRQLPPPSHQAPPP 364
            :|:               ||:.....|.||.|...:.:  |.|.......|.|....||
Human   393 MGLLTNHGGVPHQPQTDYALSPLTGGLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPP 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeobox	89..141	CDD:278475	38/51 (75%)
		OAR	374..391	CDD:281777
PAX3	NP_852124.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		PAX	34..159	CDD:128645
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	37..93
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	113..161
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	165..228		27/95 (28%)
		Homeobox	222..276	CDD:395001	39/53 (74%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	309..351		12/59 (20%)
		Pax7	347..391	CDD:403540	10/48 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910