DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment al and Pax7

DIOPT Version :9

Sequence 1:	NP_722629.1	Gene:	al / 33208	FlyBaseID:	FBgn0000061	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	XP_006239325.1	Gene:	Pax7 / 500574	RGDID:	1564360	Length:	505	Species:	Rattus norvegicus

Alignment Length:	370	Identity:	116/370 - (31%)
Similarity:	153/370 - (41%)	Gaps:	80/370 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 APSGASGASGGTNSPVSDGNSDCEADEYAP-KRKQRRYRTTFTSFQLEELEKAFSRTHYPDVFTR 115
            |.....|..|...:.:.:| ||.|::...| ||||||.|||||:.|||||||||.||||||::||
  Rat   184 AKHSIDGILGDKGNRLDEG-SDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTR 247

  Fly   116 EELAMKIGLTEARIQVWFQNRRAKWRKQEKVGPQSHPYNPYLPGGAATMQTVVGAALPPNPFTHL 180
            ||||.:..|||||:||||.||||:||||.... |...:|..||||           .||.
  Rat   248 EELAQRTKLTEARVQVWFSNRRARWRKQAGAN-QLAAFNHLLPGG-----------FPPT----- 295

  Fly   181 GFQLRKPFDAQHAANLAAFRYPHLSAAPMIPSGYFNQFQRAPPHMLPHGMAGMYSPSSSFQ-SLL 244
            |.....|:....:|      ||..:.:....|....      |..||        ||:..| .|.
  Rat   296 GMPTLPPYQLPDSA------YPTTTVSQDGGSTVHR------PQPLP--------PSTMHQGGLA 340

  Fly   245 ANMTAVPRGTPLGKPPALLVGSPDLHSP----NHMLASPPTSPASGHASQHQQHPTAHPPPPQAP 305
            |...|....:..|...:....|....:|    |||  :|.::..|........:|:|.||.|||
  Rat   341 AAAAAADSSSAYGARHSFSSYSDSFMNPGAPSNHM--NPVSNGLSPQVMSILSNPSAVPPQPQA- 402

  Fly   306 PQMPVGVQPAQLSPQH-------LVGIALTQQASSLSPTQTSPVALTLSHSPQRQLPP----PSH 359
                    ...:||.|       .:..:.:|:|.|:.|..:.|.:       |...||    ..:
  Rat   403 --------DFSISPLHGGLDSASSISASCSQRADSIKPGDSLPTS-------QSYCPPTYSTTGY 452

  Fly   360 QAPPPP-------PRAATPPEDRRTSSIAALRLKAREHELKLELL 397
            ...|..       .:.|.....:..|.....|:|..||...|.||
  Rat   453 SVDPVAGYQYSQYGQTAVDYLAKNVSLSTQRRMKLGEHSAVLGLL 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeobox	89..141	CDD:278475	39/51 (76%)
al	NP_722629.1	OAR	374..391	CDD:281777	4/16 (25%)
Pax7	XP_006239325.1	PAX	34..161	CDD:128645
		Homeobox	220..274	CDD:395001	40/53 (75%)
		Pax7	<354..385	CDD:403540	7/32 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910