DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment al and alx4b

DIOPT Version :9

Sequence 1:	NP_722629.1	Gene:	al / 33208	FlyBaseID:	FBgn0000061	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001297007.1	Gene:	alx4b / 497424	ZFINID:	ZDB-GENE-050208-140	Length:	259	Species:	Danio rerio

Alignment Length:	265	Identity:	56/265 - (21%)
Similarity:	83/265 - (31%)	Gaps:	114/265 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly   207 APMIPSGYFNQFQRAPPHMLPHGMAGMYSPSSSFQSLLANMTAVP-RGTPLGKPPALLVGSPDLH 270
            :|..|..  .:.|:|.|:.........|||           |.:| :|...|:.|         .
Zfish    20 SPAAPGQ--GRVQQANPYRTFQSSDSKYSP-----------TFLPAKGQTYGEKP---------R 62

  Fly   271 SPNHMLASPPT---SPASGHASQH---QQHPTAHPPP-----------------PQAPP------ 306
            ||.|.  ..||   |.|.|..|::   .|.|....|.                 .::|.
Zfish    63 SPFHQ--DCPTLDDSTAEGAYSKYHLFMQRPACKSPSEDSKLEDGALISCYGVVSESPGKWRKRE 125

  Fly   307 ----------------QMPVGVQP---AQL-SPQHLVGIALTQQASSLSPTQTSPVALTLSHSPQ 351
                            ::|:..:|   ||: :|..|.|      :||.||.   |..:....:..
Zfish   126 RFGQMQQVRTHFSTAYELPLLTRPENYAQIQNPSWLSG------SSSASPV---PGCVVPCDTVS 181

  Fly   352 RQLPPPSHQA---------PPPPPRAA----------------------TPPEDRRTSSIAALRL 385
            ..:.|..|.|         |.|....|                      :...||::||||:||:
Zfish   182 SCMTPHPHSASGVSDFLGMPSPGGSMAQTHMGSLFGSSGVGGTINGYDLSVEPDRKSSSIASLRM 246

  Fly   386 KAREH 390
            ||:||
Zfish   247 KAKEH 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeobox	89..141	CDD:278475
al	NP_722629.1	OAR	374..391	CDD:281777	12/17 (71%)
alx4b	NP_001297007.1	OAR	235..252	CDD:281777	12/17 (71%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D454642at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24329
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020