DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment al and repo

DIOPT Version :9

Sequence 1:	NP_722629.1	Gene:	al / 33208	FlyBaseID:	FBgn0000061	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_477026.1	Gene:	repo / 47285	FlyBaseID:	FBgn0011701	Length:	612	Species:	Drosophila melanogaster

Alignment Length:	427	Identity:	124/427 - (29%)
Similarity:	168/427 - (39%)	Gaps:	121/427 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 KLAHPDAVVLVDRAPGSSAASAGAALTV------------SMSVSGGAPSGASGASGGTNSPVS- 68
            ||..||.:.....|.|:......::.||            |.|.:|....||:|.:||..:|.:
  Fly   223 KLKKPDEMCSQLEAGGAGVTPPSSSSTVVNGTTNGTGNANSSSSAGVGIQGAAGTAGGVAAPAAK 287

  Fly    69 -DGNSDCEADEYAPKR-KQRRYRTTFTSFQLEELEKAFSRTHYPDVFTREELAMKIGLTEARIQV 131
             ||:|..:..:  |.. |:::.|||||::||||||:||.|..|||||.|||||:|:.|:|:|:||
  Fly   288 KDGSSSKKKGD--PNGIKKKKTRTTFTAYQLEELERAFERAPYPDVFAREELAIKLNLSESRVQV 350

  Fly   132 WFQNRRAKWRKQEKVGPQSHPYNPYLPGGAATMQTVVGAALPP----NPFTHLGFQLRKPFDAQH 192
            |||||||||||.|.  |:...|              :..:.||    ||.|     |..||.:
  Fly   351 WFQNRRAKWRKHEP--PRKTGY--------------IKTSTPPTATLNPGT-----LAPPFTS-- 392

  Fly   193 AANLAAFRYPHLSAAPMIPSGYFN-------------QFQRAPPHMLPHG-MAGMYSPSSSFQSL 243
                    ||..:.  :.|.|..:             ||....|...|:| .:|.|. :...:|.
  Fly   393 --------YPQTTT--VTPPGSMDSWTSYQTPYELTPQFSLLSPAASPYGTYSGQYG-AYVHESQ 446

  Fly   244 LANMTAVPRGTP----LGKPPALLVGSPDLHSPN--------------HMLASPPTSPASGHASQ 290
            |..|.....|:|    :|.....:.|:.|....|              ..||.........|..|
  Fly   447 LFPMRHYEYGSPTRMEMGATTGSVAGNGDESVANGGSYQTAELQTAQQQQLADGTLVTVHAHQQQ 511

  Fly   291 HQQHPTAHPPPPQAPPQMPVGVQPAQ------LSP-----------QHLVGIALTQQASSLSPT- 337
            .||....:.....|.....|.:|..|      |||           ||.|..| |..|:|...|
  Fly   512 QQQQQQLNGKYLSAEEAKYVHLQCHQSGGGLELSPGASCHLVEAQGQHYVTTA-TGGAASAGGTS 575

  Fly   338 ---------QTSPVALTLSHSPQRQ------LPPPSH 359
                     ||...:..:|...|:|      |||..|
  Fly   576 SDDNDSGGMQTVIKSEEVSQQQQQQQGQSYVLPPFLH 612

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeobox	89..141	CDD:278475	38/51 (75%)
al	NP_722629.1	OAR	374..391	CDD:281777
repo	NP_477026.1	Homeobox	313..360	CDD:278475	33/46 (72%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451007
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24329
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.940