Protein Alignment al and shox2

DIOPT Version :10

• Sequence 1: NP_722629.1
• Gene: al / 33208
• FlyBaseID: FBgn0000061
• Length: 408
• Species: Drosophila melanogaster
• Sequence 2: NP_957490.1
• Gene: shox2 / 394171
• ZFINID: ZDB-GENE-040426-1457
• Length: 299
• Species: Danio rerio
• Alignment Length: 352
• Identity: 104/352 - (29%)
• Similarity: 132/352 - (37%)
• Gaps: 132/352 - (37%)

  Fly    56 ASGASGGTNSP-VSDGNS-------DCE--ADEYAPKRKQRRYRTTFTSFQLEELEKAFSRTHYP 110
            ||..|..::|| ::|||:       ||:  .||...|.||||.||.||..||.|||:.|..||||
Zfish    69 ASERSRDSSSPKLTDGNTDMKERKEDCKPLEDETQTKIKQRRSRTNFTLEQLNELERLFDETHYP 133

  Fly   111 DVFTREELAMKIGLTEARIQVWFQNRRAKWRKQEKVGPQSHPYNPYLPGGAATMQTVVGAALPPN 175
            |.|.||||:.::||:|||:||||||||||.||||.   |.|  ...|.|.|:..:     |....
Zfish   134 DAFMREELSQRLGLSEARVQVWFQNRRAKCRKQEN---QLH--KGVLIGAASQFE-----ACRVA 188

  Fly   176 PFTHLGFQLRKPFDAQHAANLAAFRYPHLSAAPMIPSGYFNQFQRAPPHMLPHGMAGMYSPSSSF 240
            |:.::| .||.||......|:                                       |..||
Zfish   189 PYVNVG-ALRMPFQQDSHCNV---------------------------------------PPFSF 213

  Fly   241 QSLLANMTAVPRGTPLGKPPALLVGSPDLHSPNHMLASPPTSPASGHASQH-QQHPTAHPPPPQA 304
            |                                 :.|......|..||..| ..|..||.|....
Zfish   214 Q---------------------------------VQAQLQLDSAVAHAHHHLHSHLAAHAPYMMF 245

  Fly   305 PPQMPVGVQPAQLSPQHLVGIALTQQASSLSPTQTSPVALTLSHSPQRQLPPPSHQAPPPPPRAA 369
            |.. |.|:..|.|:         .:.||:.|....:..|.|.:
Zfish   246 PAP-PFGLPLATLA---------AESASAASVVAAAAAAKTTN---------------------- 278

  Fly   370 TPPEDRRTSSIAALRLKAREHELKLEL 396
                  :.||||.|||||::|...|.|
Zfish   279 ------KNSSIADLRLKAKKHAAALGL 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeodomain	86..142	CDD:459649	37/55 (67%)
		OAR	374..391	CDD:461067	9/16 (56%)
shox2	NP_957490.1	Homeodomain	109..165	CDD:459649	37/55 (67%)
		OAR	278..295	CDD:461067	10/44 (23%)