DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment al and gsb

DIOPT Version :9

Sequence 1:	NP_722629.1	Gene:	al / 33208	FlyBaseID:	FBgn0000061	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_523863.1	Gene:	gsb / 38005	FlyBaseID:	FBgn0001148	Length:	427	Species:	Drosophila melanogaster

Alignment Length:	391	Identity:	113/391 - (28%)
Similarity:	153/391 - (39%)	Gaps:	121/391 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 EIKLEELPQ----------EAKLAHPDAVVLVDRAPGSSAASAGAALTVSMSVSGGAPSGAS--- 57
            |.::|||.|          .|||....   :.|:....|.:|      :|..:.|.:.||.|
  Fly    99 ESRIEELKQSQPGIFSWEIRAKLIEAG---VCDKQNAPSVSS------ISRLLRGSSGSGTSHSI 154

  Fly    58 -GASGGTNSPVSDGNSDCEADEYAP----KRKQRRYRTTFTSFQLEELEKAFSRTHYPDVFTREE 117
             |..||....|  |:.|...|:..|    ||||||.||||::.|::.||:.|:||.||||:||||
  Fly   155 DGILGGGAGSV--GSEDESEDDAEPSVQLKRKQRRSRTTFSNDQIDALERIFARTQYPDVYTREE 217

  Fly   118 LAMKIGLTEARIQVWFQNRRAKWRKQEKVGPQSHP-YNPYLPGGAATMQTVVGAALPPNPFTHLG 181
            ||...||||||:||||.||||:.|||  :..|..| :.|......||..|  .||..||    :|
  Fly   218 LAQSTGLTEARVQVWFSNRRARLRKQ--LNTQQVPSFAPTSTSFGATPTT--SAAPAPN----MG 274

  Fly   182 FQLRKPFDAQHAANLAAFRYPHLSAAPMIPSGYFNQFQRAPPHMLPHGMAGMYSPSSSFQSLLAN 246
            ..|   :.:|        .:|...|       |.|       |....|.....||:||
  Fly   275 MSL---YSSQ--------SWPSSGA-------YEN-------HAAYGGSVASMSPASS------- 307

  Fly   247 MTAVPRGTPLGKPPALLVGSPDLHSPNHMLASPPTSPAS------GHASQHQQHPTAHPPPPQAP 305
                ..||           |...|||....|..|.:.:.      |..|.:..:|:|....||.|
  Fly   308 ----TSGT-----------SSAAHSPVQTQAQQPGTGSEFMTSTYGVGSSNATYPSAAYSMPQTP 357

  Fly   306 PQMPVGVQ----------------------------PAQLSPQHLVGI--ALTQQASSLSPTQTS 340
            ......::                            ||..:..|:.|.  .:.|::|.::...|.
  Fly   358 ATSAEQLRSQFASAAASGSHHPSTWDSYNFAGSFFPPASAAGNHISGYHHQVDQKSSMMTTAPTY 422

  Fly   341 P 341
            |
  Fly   423 P 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeobox	89..141	CDD:278475	34/51 (67%)
al	NP_722629.1	OAR	374..391	CDD:281777
gsb	NP_523863.1	PAX	19..143	CDD:128645	12/52 (23%)
gsb	NP_523863.1	homeodomain	186..243	CDD:238039	37/56 (66%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450980
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840