DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment al and gsb-n

DIOPT Version :9

Sequence 1:	NP_722629.1	Gene:	al / 33208	FlyBaseID:	FBgn0000061	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_523862.1	Gene:	gsb-n / 38004	FlyBaseID:	FBgn0001147	Length:	449	Species:	Drosophila melanogaster

Alignment Length:	360	Identity:	116/360 - (32%)
Similarity:	147/360 - (40%)	Gaps:	92/360 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SEEIKLEELPQEAKLAHPDAVVLVDR-APGSSAASAGAALTVSMSVSGGAPSGASGASGGTNSPV 67
            |.||: |:|.:|. .|.|.:...:.| ..||...|.          .|......:|..||.:|.:
  Fly   115 SWEIR-EKLIKEG-FADPPSTSSISRLLRGSDRGSE----------DGRKDYTINGILGGRDSDI 167

  Fly    68 SDGNSDCEADEYAP-KRKQRRYRTTFTSFQLEELEKAFSRTHYPDVFTREELAMKIGLTEARIQV 131
                ||.|::...| ||||||.|||||:.|||.||:|||||.||||:||||||....||||||||
  Fly   168 ----SDTESEPGIPLKRKQRRSRTTFTAEQLEALERAFSRTQYPDVYTREELAQTTALTEARIQV 228

  Fly   132 WFQNRRAKWRKQEKVGPQSHPYNP----------------------YLPGGAATM--------QT 166
            ||.||||:.||..  |..:...:|                      |.|.|..:|        .|
  Fly   229 WFSNRRARLRKHS--GGSNSGLSPMNSGSSNVGVGVGLSGATAPLGYGPLGVGSMAGYSPAPGTT 291

  Fly   167 VVGAALPPNPFTHLGFQLRKPFDAQHAANLAAFRYPHLSAAPMIPSGYFNQFQRAPPHMLPHGMA 231
            ..||.:  |...|  .....|.....||..||..:.|..      .|.::..|.|..|..|.|.|
  Fly   292 ATGAGM--NDGVH--HAAHAPSSHHSAATAAAAAHHHTQ------MGGYDLVQSAAQHGFPGGFA 346

  Fly   232 --GMYSPSSSFQSLLANMTAVPRGTPLGKPPALLVG--SPDLH-SPNHMLASPPT--SPASGHA- 288
              |.:...:.:....:.:|.    ....|..|..|.  ||.|| |.|:.....|:  |.|:.||
  Fly   347 QPGHFGSQNYYHQDYSKLTI----DDFSKLTADSVSKISPSLHLSDNYSKLEAPSNWSQAAYHAA 407

  Fly   289 -------SQHQQHPTA-------------HPPPPQ 303
                   :|||.:..|             ||.|.|
  Fly   408 ANYNAHVAQHQLNDYAAAAAHGNPASAYSHPLPTQ 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeobox	89..141	CDD:278475	39/51 (76%)
al	NP_722629.1	OAR	374..391	CDD:281777
gsb-n	NP_523862.1	PAX	20..141	CDD:278709	9/27 (33%)
gsb-n	NP_523862.1	Homeobox	185..238	CDD:278475	39/52 (75%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450983
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840