DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment al and otp

DIOPT Version :9

Sequence 1:	NP_722629.1	Gene:	al / 33208	FlyBaseID:	FBgn0000061	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001286654.1	Gene:	otp / 37364	FlyBaseID:	FBgn0015524	Length:	416	Species:	Drosophila melanogaster

Alignment Length:	412	Identity:	122/412 - (29%)
Similarity:	173/412 - (41%)	Gaps:	122/412 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 ELPQEAKLA-H---------PDAVVLVDRAPGSSAASAGAALTVS-----MSVSGG------APS 54
            :||:.|..| |         |....|.|...|:....:...:.|.     :.:|||      |.:
  Fly    16 DLPKAALTALHAGVNSFGQLPVGPNLADLGGGAGGGGSSGGVPVGGGVARLHISGGLCDNSNALN 80

  Fly    55 GASGASGGTNSPVSDG-----NSDCEADEYAPKRKQRRYRTTFTSFQLEELEKAFSRTHYPDVFT 114
            |.:|:||..|...::|     ||..:.|::..|.||:|:||.||..||.|||:.||:|||||:|.
  Fly    81 GGNGSSGNGNGNNNNGNGNNNNSMQQQDQHLDKNKQKRHRTRFTPAQLNELERCFSKTHYPDIFM 145

  Fly   115 REELAMKIGLTEARIQVWFQNRRAKWRKQEKVGP---------QSHPYNPYLPGGAATMQTVVGA 170
            |||:||:|||||:|:|||||||||||:|::|...         .||...|:   ||......:|.
  Fly   146 REEIAMRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRTPGALLPSHGLPPF---GANITNIAMGD 207

  Fly   171 AL-------------PPNPFTHLGF-QLRKPFDAQHAAN------------LAAFRYPHLSAAPM 209
            .|             ..||.| .|| ||.:......:.|            |.|..|.|
  Fly   208 GLCGTGMFGGDRWSVGVNPMT-AGFGQLNQSSPLSSSLNSGLNSGINMGSALGAGSYQH------ 265

  Fly   210 IPSGYFNQFQRAPPHMLPHGMAGMYSPSSSFQSLLANMTAVPRGTPLGKPPALLVGSPDLHS--- 271
                              :|:..: ..|..:|..:..::..|.|:|....|      |:::|
  Fly   266 ------------------YGLNAL-GDSMMYQHSVGGVSCGPSGSPSATTP------PNMNSCSS 305

  Fly   272 --PNHMLASPPTS-------PASGHASQ------------HQQHPTAHPPPPQAPPQMPVGVQ-P 314
              |..:.|.|.:|       |...|..|            ||.||.|.|.|.|...|:|..:| |
  Fly   306 VTPPPLSAQPNSSQNELNGEPMPLHQQQQQQTHQHQQQQTHQHHPMAPPTPTQQQQQLPQSMQSP 370

  Fly   315 AQLSPQHLVGI-ALTQQASSLS 335
            :..:...|..| ||.::||.|:
  Fly   371 SDGANDTLHSIAALRRRASELN 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeobox	89..141	CDD:278475	38/51 (75%)
al	NP_722629.1	OAR	374..391	CDD:281777
otp	NP_001286654.1	Homeobox	119..167	CDD:278475	33/47 (70%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450947
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840