DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment al and Pph13

DIOPT Version :9

Sequence 1:	NP_722629.1	Gene:	al / 33208	FlyBaseID:	FBgn0000061	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_477330.1	Gene:	Pph13 / 33239	FlyBaseID:	FBgn0023489	Length:	357	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	94/275 - (34%)
Similarity:	124/275 - (45%)	Gaps:	76/275 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 DEYAPKRKQRRYRTTFTSFQLEELEKAFSRTHYPDVFTREELAMKIGLTEARIQVWFQNRRAKWR 141
            |:...|||||||||||.:.||:|||:||.||||||||.|||||::|.|||||:||||||||||||
  Fly     2 DKGTMKRKQRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWR 66

  Fly   142 KQEKVGPQSHPY--------------------NPYLPGGAATMQTVVGAALPPNPFTHLGFQLRK 186
            ||||:|.....|                    :..|.||...:...     ||.....|..:|:
  Fly    67 KQEKIGGLGGDYKEGALDLDVSYDDSAVLGQLDSALGGGGTLLPDT-----PPQSSNSLDNELK- 125

  Fly   187 PFDAQHAANLAAFRYPHLSAAPMIPSGYFNQFQRAPPHM-LPHGMAGM------YSPSSSFQSLL 244
                      |::....:|.:.:.|:.:.|   ....|: |..|.:|:      |.|.:..|:
  Fly   126 ----------ASYGTGAMSPSRLSPNIFLN---LNIDHLGLERGGSGLSMEWSTYPPQTQAQT-- 175

  Fly   245 ANMTAVPRGTPLGKPPALLVGSPDLHSPNHMLASPPTSPAS-----GHASQHQQHPTAHPPPPQA 304
                                 .|.:.|.|.:...||...||     |.:|.|||....| ...|.
  Fly   176 ---------------------HPQMDSDNQLQQHPPQQHASDPIHAGSSSHHQQQQQQH-QQEQH 218

  Fly   305 PPQMPVGVQ-PAQLS 318
            .||:..|:: .|.||
  Fly   219 NPQLHPGLEFAASLS 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeobox	89..141	CDD:278475	40/51 (78%)
al	NP_722629.1	OAR	374..391	CDD:281777
Pph13	NP_477330.1	Homeobox	14..66	CDD:278475	40/51 (78%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451206
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	1	0.900	-	-		E33208_3BSUU
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D143142at50557
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24329
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5874
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.880