DRSC/TRiP Functional Genomics Resources

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Protein Alignment al and unc-4

DIOPT Version :9

Sequence 1:NP_722629.1 Gene:al / 33208 FlyBaseID:FBgn0000061 Length:408 Species:Drosophila melanogaster
Sequence 2:NP_001285389.1 Gene:unc-4 / 32757 FlyBaseID:FBgn0024184 Length:588 Species:Drosophila melanogaster


Alignment Length:415 Identity:113/415 - (27%)
Similarity:160/415 - (38%) Gaps:123/415 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    34 SAASAGAALTVSMSVS----------------GGAPSGASGASGGTNSPVSDGNSDCEADEYAPK 82
            |||...|...|:.:|:                .|.||..|...||.   ..||:.|..|      
  Fly   185 SAAQTTAVAAVASTVATIQHRLMIGNRQSLPPAGPPSEGSNEDGGF---PGDGDDDSSA------ 240

  Fly    83 RKQRRYRTTFTSFQLEELEKAFSRTHYPDVFTREELAMKIGLTEARIQVWFQNRRAKWRKQE--K 145
            .|:||.||.|.|:||||||:|||.:||||:|.||.|||::.|.|:|:.|||||||||.||:|  |
  Fly   241 AKRRRSRTNFNSWQLEELERAFSASHYPDIFMREALAMRLDLKESRVAVWFQNRRAKVRKREHTK 305

  Fly   146 VGPQSHPYNPYLPGGAATMQTVVGAALPPNPF-----THLGFQLRKPFDAQH--------AANLA 197
            .||....:|       |..||..|..:|||..     .....:|.|..|.|.        ..:|.
  Fly   306 KGPGRPAHN-------AQPQTCSGEPIPPNELKAKERARRRKKLAKAIDRQARKLQAKGITVDLE 363

  Fly   198 AFRYPHLSAAPMIPSGYFN-----------------------QFQRAPPHML---------PHGM 230
            |.:..::|...  .:|.|:                       ......|..|         ..|.
  Fly   364 ALKAEYISQHK--ANGTFSDSDLEDDGIQIDVVGGTDSDDEGDSDAVSPVRLGGGGGGGGGTGGG 426

  Fly   231 AGMYSPSSSFQSLLANMTAVPRGTPLGKPPALLVGSPDLHSPNHMLASPPT-----SPASGHASQ 290
            .|..:.||....|..:..:...|:.:|...:|  |||...:|..||::...     .|..|:.|:
  Fly   427 GGGGASSSLHCGLDGDGDSSRAGSFIGGGGSL--GSPSSVAPPSMLSNGAVQFGKLEPMDGNESE 489

  Fly   291 HQQHPTAHPPPPQAPPQM--PVGVQPAQLSPQH--LV--------------------------GI 325
            .:......|.|...|.:.  .:.:|.:|   ||  ||                          |.
  Fly   490 ERDRERDSPKPLLFPAKAFHQLNLQSSQ---QHHGLVVGQGQGSGSGHGHGHQHNHHQHHLHHGS 551

  Fly   326 ALTQQASSLSPT--QTSPVALTLSH 348
            |....|::::..  ||||:::..|:
  Fly   552 ASASAAAAVANLVHQTSPISMRRSN 576

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alNP_722629.1 Homeobox 89..141 CDD:278475 35/51 (69%)
OAR 374..391 CDD:281777
unc-4NP_001285389.1 Homeobox 246..299 CDD:278475 35/52 (67%)
NK <327..>368 CDD:302627 8/40 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45450918
Domainoid 1 1.000 55 1.000 Domainoid score I4097
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.840

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