Protein Alignment al and otx2b

DIOPT Version :10

• Sequence 1: NP_722629.1
• Gene: al / 33208
• FlyBaseID: FBgn0000061
• Length: 408
• Species: Drosophila melanogaster
• Sequence 2: NP_571326.1
• Gene: otx2b / 30501
• ZFINID: ZDB-GENE-980526-406
• Length: 289
• Species: Danio rerio
• Alignment Length: 295
• Identity: 89/295 - (30%)
• Similarity: 122/295 - (41%)
• Gaps: 95/295 - (32%)

  Fly    80 APKRKQRRYRTTFTSFQLEELEKAFSRTHYPDVFTREELAMKIGLTEARIQVWFQNRRAKWRKQE 144
            |..|||||.|||||..||:.||..|::|.|||:|.|||:|:||.|.|:|:||||:|||||.|:|
Zfish    33 ATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ- 96

  Fly   145 KVGPQSHPYNPYLPGGAATMQTVVGAALPPNPFTHLGFQLRKPFDAQHAANLAAFRYPHLSAAPM 209
                |....|    ||    |..|..|            .:|...|:.|::
Zfish    97 ----QQQQQN----GG----QNKVRPA------------KKKSSPAREASS-------------- 123

  Fly   210 IPSGYFNQFQRAPPHMLPHGMAGMYSPSSSFQSLLANMTAVPRGTPLGKPPALLVGSPDLHSPNH 274
                             ..|.:|.::|.||        |:||..:....|  :.:.||...||
Zfish   124 -----------------ESGASGQFTPPSS--------TSVPAISTTTAP--VSIWSPASISP-- 159

  Fly   275 MLASPPTSPASGHASQHQQHPTAHPPPPQAPPQ-------------MPVGVQPAQLSPQHLVGIA 326
              .|.|.|.:|  :...:.:|..:   .||...             |..|   :.|:|.|   ..
Zfish   160 --LSDPLSTSS--SCMQRSYPMTY---TQASGYSQGYAGSTSYFGGMDCG---SYLTPMH---HQ 211

  Fly   327 LTQQASSLSPTQTSPVALTLSHSPQRQLPPPSHQA 361
            ||...|:|||..::.|...|:.|| ..||...:.|
Zfish   212 LTGPGSTLSPMSSNAVTSHLNQSP-ASLPTQGYGA 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeodomain	86..142	CDD:459649	35/55 (64%)
		OAR	374..391	CDD:461067
otx2b	NP_571326.1	Homeodomain	39..94	CDD:459649	35/54 (65%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	93..142		20/112 (18%)
		TF_Otx	153..234	CDD:427350	24/95 (25%)