DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment al and Pax2

DIOPT Version :9

Sequence 1:	NP_722629.1	Gene:	al / 33208	FlyBaseID:	FBgn0000061	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	XP_006231505.2	Gene:	Pax2 / 293992	RGDID:	1305568	Length:	432	Species:	Rattus norvegicus

Alignment Length:	367	Identity:	85/367 - (23%)
Similarity:	119/367 - (32%)	Gaps:	147/367 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 PDAVVLVDRAPGSSAASAGAALTV---------SMSVSG--GAPSG----------------ASG 58
            ||.......|||.:...:.|:..|         |.|::|  |.|..                |..
  Rat   151 PDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKREEVEVYTDPAHI 215

  Fly    59 ASGG-----------TNSPVSDGNSDCEADEYAPKRKQRRYRTTFTSFQLEELEKAFSRTHYPDV 112
            ..||           :...|.:|:|....|..   ||..| ..|||..|||.|::.|.|..||||
  Rat   216 RGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSL---RKHLR-ADTFTQQQLEALDRVFERPSYPDV 276

  Fly   113 FTREELAMKIGLTEARIQVWFQNRRAKWRKQEKVGPQSHPYN-PYLPGGAATMQTVVGAALPPNP 176
            |...|..                      |.|    |.:.|: |.|..|...:::.:.|:..|
  Rat   277 FQASEHI----------------------KSE----QGNEYSLPALTPGLDEVKSSLSASTNP-- 313

  Fly   177 FTHLGFQLRKPFDAQHAANLAAFR-YPHLSAAPMIPS---GYFNQFQRAPPHMLPHGMAGMYSPS 237
              .||            :|::..: ||.::...|..:   ||       |||:.|.|. |.| |:
  Rat   314 --ELG------------SNVSGTQTYPVVTGRDMASTTLPGY-------PPHVPPTGQ-GSY-PT 355

  Fly   238 SSFQSLLANMTAVPRGTPLGKPPALLVGSPDLHSPNHMLASPPTSPASGHASQHQQH-------- 294
            |:    ||.|.                               |.|..||:...|.|:
  Rat   356 ST----LAGMV-------------------------------PGSEFSGNPYSHPQYTAYNEAWR 385

  Fly   295 ---PTAHPPPPQAPPQMPVGVQPAQLSPQHLVGIALTQQASS 333
               |....|||.||| :|  :.|..::.....|..:..||.|
  Rat   386 FSNPALLMPPPGAPP-LP--LLPLPMTATSYRGDHIKLQADS 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeobox	89..141	CDD:278475	15/51 (29%)
al	NP_722629.1	OAR	374..391	CDD:281777
Pax2	XP_006231505.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910