DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment al and sebox

DIOPT Version :9

Sequence 1:	NP_722629.1	Gene:	al / 33208	FlyBaseID:	FBgn0000061	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001306981.1	Gene:	sebox / 282666	ZFINID:	ZDB-GENE-021206-4	Length:	293	Species:	Danio rerio

Alignment Length:	307	Identity:	87/307 - (28%)
Similarity:	109/307 - (35%)	Gaps:	92/307 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 NSPVSDGNSDCEADEYAPKRKQRRYRTTFTSFQLEELEKAFSRTHYPDVFTREELAMKIGLTEAR 128
            :||..|.....|.       :::|.||.|:..||.|||:||..|.|||:..||.||....|.|::
Zfish    44 SSPELDRTGHVEG-------QRKRKRTIFSRAQLSELERAFMITPYPDITLRERLAALTLLPESK 101

  Fly   129 IQVWFQNRRAKWRKQEKVGPQSHPYNPYLPGGAATMQTVVGAALPPNPFTHLGFQLRKPFDAQHA 193
            ||||||||||:..|.:|                  :.|.|....|....|         |.|.|
Zfish   102 IQVWFQNRRARSMKSKK------------------LITPVSRRSPAKDCT---------FPATH- 138

  Fly   194 ANLAAFRYPHLSAAPMIPSGYFNQFQRAPPHMLPHGMAGMYSPSSSFQSLLANMTAVPRGTPLGK 258
                    |.|:         ..|...|...:..|            |..|......|  .|..:
Zfish   139 --------PDLN---------LEQSPEANKSLRHH------------QQSLIRQALNP--WPQNR 172

  Fly   259 PPALLVGSPDLHS----PNHMLASPPTSPASGHASQHQQHPTAHPPPPQAPPQMPVGVQPAQLSP 319
            ||.    ||||..    .|....:|..|..|...|:..|||.    |.|:.....:....|.  |
Zfish   173 PPI----SPDLPEILQWANRNSETPGDSSFSSCPSERIQHPF----PNQSSSVWQMNCFAAH--P 227

  Fly   320 QHLVGIALTQQA--SSLSPTQTSPV-------AL---TLSHSPQRQL 354
            :.|.....|.||  ||:|..|..|.       ||   .|:|.||..|
Zfish   228 EGLKSYCTTSQALYSSVSVDQMIPAHPSSLEEALQRQALTHYPQTSL 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeobox	89..141	CDD:278475	30/51 (59%)
al	NP_722629.1	OAR	374..391	CDD:281777
sebox	NP_001306981.1	COG5576	13..159	CDD:227863	50/178 (28%)
		Homeobox	61..112	CDD:278475	29/50 (58%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	117..144		10/71 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24329
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010