DRSC/TRiP Functional Genomics Resources

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Protein Alignment al and Pax5

DIOPT Version :9

Sequence 1:NP_722629.1 Gene:al / 33208 FlyBaseID:FBgn0000061 Length:408 Species:Drosophila melanogaster
Sequence 2:NP_032808.1 Gene:Pax5 / 18507 MGIID:97489 Length:391 Species:Mus musculus


Alignment Length:322 Identity:80/322 - (24%)
Similarity:120/322 - (37%) Gaps:107/322 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 KLEELPQEAKLAHPDAVV---LVDRAPGSSAASAGAALTVSMSVSGGAPSGASGA----SGGTNS 65
            |:::.|.:...|...::|   .|.:....|..|||::.::|..:...:||..:..    .|...|
Mouse   142 KVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISGILGITSPSADTNKRKRDEGIQES 206

  Fly    66 PVSDGNSDCEADEYAPKRKQRRYRTTFTSFQLEELEKAFSRTHYPDVFTREELAMKIGLTEARIQ 130
            ||.:|:|....|..   |||.| ...||..|||.|::.|.|.||.|:||                
Mouse   207 PVPNGHSLPGRDFL---RKQMR-GDLFTQQQLEVLDRVFERQHYSDIFT---------------- 251

  Fly   131 VWFQNRRAKWRKQEKVGP-QSHPYNPY--LPGGAATMQTVVGAALPPNPFTHLGFQLRKPFDAQH 192
                       ..|.:.| |:..|:..  |.||...|:..:.:..|.:    :|..:..|..   
Mouse   252 -----------TTEPIKPEQTTEYSAMASLAGGLDDMKANLTSPTPAD----IGSSVPGPQS--- 298

  Fly   193 AANLAAFRYPHLS----AAPMIPSGYFNQFQRAPPHMLPHGMAGMYS--------PSSSFQSLLA 245
                    ||.::    |:..:| ||       |||:.|.|. |.||        |.|.|.    
Mouse   299 --------YPIVTGRDLASTTLP-GY-------PPHVPPAGQ-GSYSAPTLTGMVPGSEFS---- 342

  Fly   246 NMTAVPRGTPLGKP-------------PALLVGSPDLHSPNHMLASPPTSPASGHASQHQQH 294
                   |:|...|             |.|| |||..:||....|:||.:     |:.:.:|
Mouse   343 -------GSPYSHPQYSSYNDSWRFPNPGLL-GSPYYYSPAARGAAPPAA-----ATAYDRH 391

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alNP_722629.1 Homeobox 89..141 CDD:278475 13/51 (25%)
OAR 374..391 CDD:281777
Pax5NP_032808.1 PAX 16..140 CDD:128645
PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381 19..75
RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381 94..142 80/322 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 182..218 9/35 (26%)
Pax2_C 285..389 CDD:289189 35/144 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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