DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment al and unc-4

DIOPT Version :9

Sequence 1:	NP_722629.1	Gene:	al / 33208	FlyBaseID:	FBgn0000061	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_496138.1	Gene:	unc-4 / 174544	WormBaseID:	WBGene00006744	Length:	252	Species:	Caenorhabditis elegans

Alignment Length:	166	Identity:	63/166 - (37%)
Similarity:	85/166 - (51%)	Gaps:	33/166 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 VLVDRAPGSSAASAGAALTVSMSVSGGAPSGASGASGGTNSPVSDGN------------SDCEAD 77
            ||::.:.||....|             :.:|.|.:|...::...|.|            .|.:..
Worm    31 VLLNPSDGSETYLA-------------SDNGKSTSSREQSTSPDDDNLLMNEDDGIALEDDNDTG 82

  Fly    78 EYAPKRKQRRYRTTFTSFQLEELEKAFSRTHYPDVFTREELAMKIGLTEARIQVWFQNRRAKWRK 142
            |.|.||  ||.||.|:.:||||||.||..:||||||.||.|||::.|.|:|:|||||||||||||
Worm    83 ESAAKR--RRTRTNFSGWQLEELESAFEASHYPDVFMREALAMRLDLLESRVQVWFQNRRAKWRK 145

  Fly   143 QEKVGPQSHPYNPYLPGGAATMQTVVGAALPPNPFT 178
            :|:   ..:..:.........|:|   .|||..||:
Worm   146 REQ---NRNGSSEIKKDDGEQMET---KALPTFPFS 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeobox	89..141	CDD:278475	35/51 (69%)
al	NP_722629.1	OAR	374..391	CDD:281777
unc-4	NP_496138.1	COG5576	<79..186	CDD:227863	52/105 (50%)
unc-4	NP_496138.1	Homeobox	91..144	CDD:278475	35/52 (67%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910