DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment al and RHOXF1

DIOPT Version :9

Sequence 1:	NP_722629.1	Gene:	al / 33208	FlyBaseID:	FBgn0000061	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	XP_011529583.1	Gene:	RHOXF1 / 158800	HGNCID:	29993	Length:	212	Species:	Homo sapiens

Alignment Length:	147	Identity:	48/147 - (32%)
Similarity:	70/147 - (47%)	Gaps:	8/147 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 EIKLEELPQEAKLAHPDAVVLVDRAP---GSSAASAGAALTVSMSVSGG-APSGASGASGGTNSP 66
            ::|:...||....:..:..| ...||   |:.....|......|:..|| .|.|..|.......|
Human    46 QVKISPTPQLGAASSAEGHV-GQGAPGLMGNMNPEGGVNHENGMNRDGGMIPEGGGGNQEPRQQP 109

  Fly    67 VSDGNSDCEADEYAPK---RKQRRYRTTFTSFQLEELEKAFSRTHYPDVFTREELAMKIGLTEAR 128
            ........:|....|:   .:.|..||.||..|:||||..|..|.||||.||.|||..:|:||.:
Human   110 QPPPEEPAQAAMEGPQPENMQPRTRRTKFTLLQVEELESVFRHTQYPDVPTRRELAENLGVTEDK 174

  Fly   129 IQVWFQNRRAKWRKQEK 145
            ::|||:|:||:.|:.::
Human   175 VRVWFKNKRARCRRHQR 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeobox	89..141	CDD:278475	29/51 (57%)
al	NP_722629.1	OAR	374..391	CDD:281777
RHOXF1	XP_011529583.1	homeodomain	132..190	CDD:238039	31/57 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910