DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment al and pax10

DIOPT Version :9

Sequence 1:	NP_722629.1	Gene:	al / 33208	FlyBaseID:	FBgn0000061	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001373372.1	Gene:	pax10 / 100192208	ZFINID:	ZDB-GENE-081022-10	Length:	275	Species:	Danio rerio

Alignment Length:	270	Identity:	86/270 - (31%)
Similarity:	108/270 - (40%)	Gaps:	80/270 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 LTVSMSVSGGAPSGASGASGGTNSPVSDGNSDCEADEYAPKRKQRRYRTTFTSFQLEELEKAFSR 106
            |.|.|:.:|      .|...|....|.|.....:.     |||.:|.||:||..|::.|||.|.|
Zfish    42 LNVQMAGAG------EGVVQGERDEVDDSQLHLQL-----KRKLQRNRTSFTQEQIDALEKEFER 95

  Fly   107 THYPDVFTREELAMKIGLTEARIQVWFQNRRAKWRKQEKVGPQSHPYNPYLPGGAATMQTVVGAA 171
            |||||||.||.||.||.|.||||||||.|||||||::||:..|...     ...::..||
Zfish    96 THYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRS-----GSSSSCSQT----- 150

  Fly   172 LPPNPFTHLGFQLRKPFDAQHAANLAAFRYPHLSAAPMIPSGY-----FNQFQRAPPHMLPHGMA 231
                 .|.|......|....|.:|.:...:   |.:....|||     |:..|..|....|
Zfish   151 -----HTPLSTSFNSPVYHSHHSNSSGSMH---SRSDSSLSGYSSLSVFSSMQSLPSQSTP---- 203

  Fly   232 GMYSPSSSFQSLLANMTAVPRGTPLGKPPALLVGSPDLHSPNHMLASPPTSPA--SGHASQHQQH 294
                   ::..:|              ||          ||:   |.||.|..  |.:.|.|.
Zfish   204 -------TYSCML--------------PP----------SPS---ALPPLSRKFDSSYTSPHL-- 232

  Fly   295 PTAHPPPPQA 304
                ||||.|
Zfish   233 ----PPPPTA 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeobox	89..141	CDD:278475	37/51 (73%)
al	NP_722629.1	OAR	374..391	CDD:281777
pax10	NP_001373372.1	Homeobox	78..131	CDD:395001	38/52 (73%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910