DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment al and phox2b

DIOPT Version :9

Sequence 1:	NP_722629.1	Gene:	al / 33208	FlyBaseID:	FBgn0000061	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001116492.1	Gene:	phox2b / 100124329	XenbaseID:	XB-GENE-1000415	Length:	293	Species:	Xenopus tropicalis

Alignment Length:	276	Identity:	91/276 - (32%)
Similarity:	119/276 - (43%)	Gaps:	104/276 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SSAASAGAALTVSMSVSG----------GAPSGASGASGGTNSPVSDGN-SDCEADEYA------ 80
            ||.|||.|..:.....||          ||.||....:.|:   .|.|. .|.::..||
Frog    24 SSLASAYADFSSCSQASGFQYNPIRTTFGATSGCPSLTPGS---CSLGTLRDHQSSPYAAVPYKL 85

  Fly    81 --------PKRKQRRYRTTFTSFQLEELEKAFSRTHYPDVFTREELAMKIGLTEARIQVWFQNRR 137
                    .||||||.||||||.||:|||:.|:.|||||::||||||:||.|||||:||||||||
Frog    86 FTDHGGLNEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRR 150

  Fly   138 AKWRKQEKV-------------------------------------GPQSHPYNPY--------- 156
            ||:||||:.                                     ||.::| ||.
Frog   151 AKFRKQERAAAAAAAAAKNGSSGKKSDSSRDEESKDSKSADPDSTGGPGNNP-NPTPSCGGGPSP 214

  Fly   157 ----------------LPG-GAATMQTVVG--------AALPPNPFTHLGFQLRKPFDAQHAANL 196
                            :|| |:.|..:|||        |..|....|.:...|..||    |:.|
Frog   215 SGAQGNGVPQEPGKVGVPGPGSLTSASVVGVSGGPQGWATGPGGTITSIPDSLGGPF----ASVL 275

  Fly   197 AAFRYPHLSAAPMIPS 212
            ::.:.|:.:.|.::.|
Frog   276 SSLQRPNSTKATLVKS 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
al	NP_722629.1	Homeobox	89..141	CDD:278475	40/51 (78%)
al	NP_722629.1	OAR	374..391	CDD:281777
phox2b	NP_001116492.1	Homeobox	102..154	CDD:278475	40/51 (78%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910