Protein Alignment Ent1 and FUN26

DIOPT Version :9

• Sequence 1: NP_001259820.1
• Gene: Ent1 / 33207
• FlyBaseID: FBgn0031250
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_009380.1
• Gene: FUN26 / 851211
• SGDID: S000000020
• Length: 517
• Species: Saccharomyces cerevisiae
• Alignment Length: 496
• Identity: 118/496 - (23%)
• Similarity: 233/496 - (46%)
• Gaps: 85/496 - (17%)

  Fly    35 DHHADEQ--CLMERQQDEVVLVSNEP-------ESGRLFTYLVFYLLGIGTMTPWNFFVTAEDYW 90
            :.|:||:  ...||:|.    ||.||       :..:..:|:.|:.:|||.:.|||..::|..|:
Yeast    42 NEHSDEEGDNYSEREQS----VSTEPLDTLPLRKKLKNLSYITFFAIGIGLLWPWNCILSASQYF 102

  Fly    91 KYK-FRNASINNTDLEEELTPLQKSFTCDLALTATISGTTFLLLNAIFGHHVSLRTKMLGTLWMI 154
            |:. |::.||           ..|.||..:...:|||...|.:..|...:..|.|. :.|.:|.|
Yeast   103 KHDIFKDTSI-----------WAKIFTSSMMSFSTISSMLFNIYLAKRQYKYSRRV-INGLVWEI 155

  Fly   155 LILFGVTTGFVEIN--TDTWQEQFFLITLIIVVLLNISAATMSGALYGVAGLFPSEFITAVVSGQ 217
             |:|.|...|..::  ...|..  |:..:::||:.::..|.....:..:|.:|.||:...|:.||
Yeast   156 -IVFTVMCFFTILHFLLPKWFN--FMFIMMLVVISSMGTAMTQNGIMAIANVFGSEYSQGVMVGQ 217

  Fly   218 ALGGILTALAFILVLAF--DTGPNTTA--FIFFIVGGVLILLCIVCYVI--LARKPFFRYYLEGG 276
            |:.|:|.:|. :..|||  ::..:||.  .::|....:::.:|:|.:.:  ::||....:.:|.|
Yeast   218 AVAGVLPSLV-LFALAFIENSSVSTTGGILLYFFTTTLVVTICVVMFSVSKISRKVNENWNVEDG 281

  Fly   277 --------------DKYKVIRAV-----PSHNR-------NGSAEGLPLEPILRQVMSKIYLHAI 315
                          ::.:::..:     ..|.|       |...|.|.|:.....:.:|:....:
Yeast   282 HITDVLLGSLRSNEEEIRIVGRIDQMEDEDHRRTNGTRDDNDEGEELQLKVPFEVLFAKLKYLVL 346

  Fly   316 SLALLYTTTLSVYPAVTVLMQSEYGHSV-WTDVYFLPVVNYLIFNCGDYFGRLFAGW---MERPL 376
            |:...:..|| |:|   |...:.|...: .::..::|:: :.::|.||.:||:.|.|   .::..
Yeast   347 SIFTTFVVTL-VFP---VFASATYVTGLPLSNAQYIPLI-FTLWNLGDLYGRVIADWPMFRDQKF 406

  Fly   377 NQNTSLLFIVVRMAFVPLFL--------CSNSSEHSFLPVLVKHDYTFIAMMVMFALSNGYFTNI 433
            ....:.::.::|:|.:||||        .|...||:...::   |..::.:..:|.::||:..::
Yeast   407 TPRKTFIYSLLRVAAIPLFLMFTAITSSSSGDEEHNGSVIV---DLCYMLLQFLFGVTNGHVISM 468

  Fly   434 LLIMAPKRV-KQHEKELASSIMAAALSCGMAVGSLLSLVFV 473
            ..:..|::: ...|||.|.......:|.|:|:||::|.|||
Yeast   469 SFMKVPEQLDNDDEKEAAGGFTNIFVSTGLALGSIISYVFV 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ent1	NP_001259820.1	Nucleoside_tran	69..476	CDD:301621	107/453 (24%)
FUN26	NP_009380.1	2a57	81..514	CDD:273352	107/453 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343788
Domainoid	1	1.000	88	1.000	Domainoid score	I1830
eggNOG	1	0.900	-	-		E1_KOG1479
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37985
Inparanoid	1	1.050	121	1.000	Inparanoid score	I1309
Isobase	1	0.950	-	0	Normalized mean entropy	S3732
OMA	1	1.010	-	-		QHG53699
OrthoFinder	1	1.000	-	-		FOG0000541
OrthoInspector	1	1.000	-	-		otm46784
orthoMCL	1	0.900	-	-		OOG6_100863
Panther	1	1.100	-	-	LDO	PTHR10332
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2123
SonicParanoid	1	1.000	-	-		X296
TreeFam	1	0.960	-	-
	16	15.740