DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ent1 and Slc29a2

DIOPT Version :9

Sequence 1:	NP_001259820.1	Gene:	Ent1 / 33207	FlyBaseID:	FBgn0031250	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_113926.1	Gene:	Slc29a2 / 65194	RGDID:	69296	Length:	456	Species:	Rattus norvegicus

Alignment Length:	458	Identity:	151/458 - (32%)
Similarity:	239/458 - (52%)	Gaps:	43/458 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 NEPESGRLFTYLVFYLLGIGTMTPWNFFVTAEDYWKYKFRNASINN---TDLEEELTPLQK-SFT 116
            |.|........:.|::||:||:.|||||:||..|  ::.|.|..|:   |......:|... :|.
  Rat     5 NAPRDSYHLVGISFFILGLGTLLPWNFFITAIPY--FQGRLAGTNSSAETPSTNHTSPTDTFNFN 67

  Fly   117 CDLALTATISGTTFLLLNAIFGHHVSLRTKMLGTLWMILILFGVTTGFVEINTDTWQEQFFLITL 181
            ..:.|.:.:....|.|||:.....:....::||:|..||:||.:|...|::  |.....||.||:
  Rat    68 NWVTLLSQLPLLLFTLLNSFLYQCIPESVRILGSLLAILLLFALTAALVKV--DLSPGLFFSITM 130

  Fly   182 IIVVLLNISAATMSGALYGVAGLFPSEFITAVVSGQALGGILTALAFILVLAFDTGPNTTAFIFF 246
            ..|..:|...|.:.|:|:|..|..||.:.|..:|||.|.||..|||.:..||....|.|:|..:|
  Rat   131 ASVWFINSFCAVLQGSLFGQLGTMPSTYSTLFLSGQGLAGIFAALAMLTSLASGVDPQTSALGYF 195

  Fly   247 IVGGVLILLCIVCYVILARKPFFRYYLE-----------------GGDKYKVI-----RAVPSHN 289
            |...|.|||.|:||:.|....|.||||.                 |.|:...|     :|.|:.:
  Rat   196 ITPCVGILLSIICYLSLPHLKFARYYLTKKPQAPVQELETKAELLGADEKNGIPVSPQQAGPTLD 260

  Fly   290 RNGSAE---GL-----PLEPILRQVMSKIYLHAISLALLYTTTLSVYPAVTVLM-QSEYGHSVWT 345
            .:...|   ||     |.:|.:..|..||:|.|:.|.|::|.||||:||:|.:: .|......|:
  Rat   261 LDPEKELELGLEEPQKPGKPSVFVVFRKIWLTALCLVLVFTVTLSVFPAITAMVTTSSNSPGKWS 325

  Fly   346 DVYFLPVVNYLIFNCGDYFGRLFAGWMERPLNQNTSL--LFIVVRMAFVPLFLCSNSSEHSFLPV 408
            . :|.|:..:|:||..|:.||....:...| ::::.|  |.:.:|..|||||:..:..:.:.||:
  Rat   326 Q-FFNPICCFLLFNVMDWLGRSLTSYFLWP-DEDSQLLPLLVCLRFLFVPLFMLCHVPQRARLPI 388

  Fly   409 LVKHDYTFIAMMVMFALSNGYFTNILLIMAPKRVKQHEKELASSIMAAALSCGMAVGSLLSLVFV 473
            :...|..||..|::||:|||||.::.:.:||::|..||:|:|.::|...|:.|::.|:.||.:|.
  Rat   389 IFWQDAYFITFMLLFAISNGYFVSLTMCLAPRQVLPHEREVAGALMTFFLALGLSCGASLSFLFK 453

  Fly   474 QML 476
            .:|
  Rat   454 ALL 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ent1	NP_001259820.1	Nucleoside_tran	69..476	CDD:301621	148/443 (33%)
Slc29a2	NP_113926.1	2a57	18..456	CDD:273352	148/443 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	173	1.000	Domainoid score	I3597
eggNOG	1	0.900	-	-		E1_KOG1479
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	233	1.000	Inparanoid score	I3336
OMA	1	1.010	-	-		QHG53699
OrthoDB	1	1.010	-	-		D318009at33208
OrthoFinder	1	1.000	-	-		FOG0000541
OrthoInspector	1	1.000	-	-		otm45393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10332
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X296
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.980