Protein Alignment Ent1 and SLC29A1

DIOPT Version :10

• Sequence 1: NP_608519.2
• Gene: Ent1 / 33207
• FlyBaseID: FBgn0031250
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: XP_011512643.1
• Gene: SLC29A1 / 2030
• HGNCID: 11003
• Length: 536
• Species: Homo sapiens
• Alignment Length: 509
• Identity: 157/509 - (30%)
• Similarity: 260/509 - (51%)
• Gaps: 48/509 - (9%)

  Fly     6 DTRRLVDALDEDDEILGTEGSFVPAFRPQDHHADE-----QCLMERQQDEVVL-VSNEPESGRLF 64
            |.|.|.:....:|: ..||.|:....|.....|.:     .|...:.::.:.: .|::|:.....
Human    30 DLRELREGEKPEDQ-AETEESWQGLARKTPGKACQAPEGGSCQPGKTENTITMTTSHQPQDRYKA 93

  Fly    65 TYLVFYLLGIGTMTPWNFFVTAEDYWKYKF---RNASINNTDLEE-------------ELTPLQK 113
            .:|:|::||:||:.|||||:||..|:..:.   :|.|:...:|.:             |...|..
Human    94 VWLIFFMLGLGTLLPWNFFMTATQYFTNRLDMSQNVSLVTAELSKDAQASAAPAAPLPERNSLSA 158

  Fly   114 SFTCDLALTATISGTTFLLLNAIFGHHVSLRTKMLGTLWMILILFGVTTGFVEINTDTWQEQFFL 178
            .|...:.|.|.:....|..||:.....:....::||:|..||::|.:|...|::..|..  .||:
Human   159 IFNNVMTLCAMLPLLLFTYLNSFLHQRIPQSVRILGSLVAILLVFLITAILVKVQLDAL--PFFV 221

  Fly   179 ITLIIVVLLNISAATMSGALYGVAGLFPSEFITAVVSGQALGGILTALAFILVLAFDTGPNTTAF 243
            ||:|.:||:|...|.:.|:|:|:|||.|:.:...::|||.|.|...::|.|..:|..:..:.:||
Human   222 ITMIKIVLINSFGAILQGSLFGLAGLLPASYTAPIMSGQGLAGFFASVAMICAIASGSELSESAF 286

  Fly   244 IFFIVGGVLILLCIVCYVILARKPFFRYY----LEG-GDKYKVIRAVP--SHNRNGSAE-GLPL- 299
            .:||....:|:|.|:||:.|.|..|:|||    ||| |::...:..:.  ...|.|..| |:.:
Human   287 GYFITACAVIILTIICYLGLPRLEFYRYYQQLKLEGPGEQETKLDLISKGEEPRAGKEESGVSVS 351

  Fly   300 --EPI-----LRQVMSKIYLHAISLALLYTTTLSVYPAVTVLMQSEY-GHSVWTDVYFLPVVNYL 356
              :|.     ::.::..|.:.|.|:..::|.|:.::|||||.::|.. |.|.| :.||:||..:|
Human   352 NSQPTNESHSIKAILKNISVLAFSVCFIFTITIGMFPAVTVEVKSSIAGSSTW-ERYFIPVSCFL 415

  Fly   357 IFNCGDYFGRLFAG---WMERPLNQNTSLLFIVVRMAFVPLFLCSNSSEHSFLPVLVKHDYTFIA 418
            .||..|:.||....   |..:......||  ::.|:.||||.|..|.....:|.|:.:||..||.
Human   416 TFNIFDWLGRSLTAVFMWPGKDSRWLPSL--VLARLVFVPLLLLCNIKPRRYLTVVFEHDAWFIF 478

  Fly   419 MMVMFALSNGYFTNILLIMAPKRVKQHEKELASSIMAAALSCGMAVGSLLSLVF 472
            .|..||.||||..::.:...||:||..|.|.|.:|||..|..|:|:|::.|.:|
Human   479 FMAAFAFSNGYLASLCMCFGPKKVKPAEAETAGAIMAFFLCLGLALGAVFSFLF 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ent1	NP_608519.2	Nucleoside_tran	69..476	CDD:472807	144/440 (33%)
SLC29A1	XP_011512643.1	2a57	98..536	CDD:273352	144/440 (33%)