DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ent1 and slc29a1b

DIOPT Version :9

Sequence 1:	NP_001259820.1	Gene:	Ent1 / 33207	FlyBaseID:	FBgn0031250	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_005172990.1	Gene:	slc29a1b / 100331439	ZFINID:	ZDB-GENE-130415-4	Length:	436	Species:	Danio rerio

Alignment Length:	423	Identity:	140/423 - (33%)
Similarity:	233/423 - (55%)	Gaps:	20/423 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 YLVFYLLGIGTMTPWNFFVTAEDYWKYK-------FRNASINNTDLEEELTPLQKSFTCDLALTA 123
            :|:|::||:||:.|||||:||..|:..:       ..|||:|:|: |:..:.||..|...:.|.|
Zfish    14 WLIFFMLGLGTLLPWNFFMTATMYFTSRLADPLTAMNNASMNSTE-EDSRSVLQAKFNNVMTLCA 77

  Fly   124 TISGTTFLLLNAIFGHHVSLRTKMLGTLWMILILFGVTTGFVEINTDTWQEQFFLITLIIVVLLN 188
            .:....|..||:|....:..:.::.|:|.:||::|.:|...|:|:.:..  .||::|::.::.:|
Zfish    78 MVPLLVFTCLNSILHQRIPQKIRIAGSLTLILLVFLLTAILVKIHLEPL--PFFIVTMVKIIFIN 140

  Fly   189 ISAATMSGALYGVAGLFPSEFITAVVSGQALGGILTALAFILVLAFDTGPNTTAFIFFIVGGVLI 253
            ...|.:.|:|:|:|||.|:.:.|.::|||.|.|...|.:.|..:|..:..:.:||.:||....:|
Zfish   141 SFGAVLQGSLFGMAGLLPASYTTPIMSGQGLAGTFAAFSMICAIASGSELHDSAFGYFITACAVI 205

  Fly   254 LLCIVCYVILARKPFFRYYLE------GGDKYKVIRAVPSHNRNGSA-EGLPLEPILRQVMSKIY 311
            .|.|..||:|.:..|:::|.|      ..|:...:..:....|..|| :.....|.:..:..||:
Zfish   206 SLAIASYVVLPKLEFYQHYQESRQNKPAEDEENKMDLLKKDQRLQSAGDDDKKSPSILAIFKKIW 270

  Fly   312 LHAISLALLYTTTLSVYPAVTVLMQSEYGHSVWTDVYFLPVVNYLIFNCGDYFGRLFAGWMERPL 376
            :.|:|:...:|.|:..:|||||.::|........:.||:||..:|.||..|:.||........|
Zfish   271 VMALSVCFAFTITIGTFPAVTVDVKSTIADGGAWEKYFIPVSCFLFFNVFDWAGRSLTAVCMWP- 334

  Fly   377 NQNTSLL--FIVVRMAFVPLFLCSNSSEHSFLPVLVKHDYTFIAMMVMFALSNGYFTNILLIMAP 439
            .:::.||  .::.|:.|||||:..|......|||...||..|||.|::||.||||..::.:...|
Zfish   335 GKDSKLLPALLLARVVFVPLFMLCNVQPRYNLPVFFTHDGWFIAFMILFAFSNGYLASLCMCFGP 399

  Fly   440 KRVKQHEKELASSIMAAALSCGMAVGSLLSLVF 472
            |:|...|.|.|.:|||..||.|:|:|:.||.:|
Zfish   400 KKVDPSEAETAGAIMAFFLSLGLALGASLSFLF 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ent1	NP_001259820.1	Nucleoside_tran	69..476	CDD:301621	139/420 (33%)
slc29a1b	XP_005172990.1	2a57	17..436	CDD:273352	139/420 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	180	1.000	Domainoid score	I3450
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37985
Inparanoid	1	1.050	240	1.000	Inparanoid score	I3316
OMA	1	1.010	-	-		QHG53699
OrthoDB	1	1.010	-	-		D318009at33208
OrthoFinder	1	1.000	-	-		FOG0000541
OrthoInspector	1	1.000	-	-		otm25782
orthoMCL	1	0.900	-	-		OOG6_100863
Panther	1	1.100	-	-	O	PTHR10332
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X296
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.980